确定血压身高比作为埃及儿童高血压筛查工具的准确性

S. Bahgat
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摘要

背景:儿童高血压诊断是困难的,因为有多种性别、年龄和身高特异性阈值来定义血压升高(BP)。血压身高比(BPHR)已被用于儿童血压升高的识别。方法:2017年1 - 6月,对埃及Sharkia省Abu Kabir市830名12 - 15岁青少年进行横断面研究。来自国家高血压教育计划(NHBPEP)儿童和青少年高血压工作组的血压表被用作我们的比较标准。计算不同性别的收缩压和舒张压高比(SBPHR和DBPHR)。采用受试者工作特征(ROC)曲线分析来评估BPHR在区分高血压和非高血压青少年中的准确性。结果:高血压前期患病率为8.4%,高血压患病率为4.9%。男性SBPHR和DBPHR的最佳阈值分别为0.741和0.475,女性为0.750和0.494。SBPHR和DBPHR在两性中的敏感性均在93%以上,特异性均在94%以上。男性SBPHR和DBPHR阳性预测值均为76.4%;女性分别为71.4%和71.6%;阴性预测值均在98%以上。结论:BPHR是一种简便、敏感、特异的青少年高血压筛查工具。
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Determining the Accuracy of Blood Pressure to Height Ratio as a Screening Tool for Hypertension among Egyptian Children
Background: Hypertension diagnosis in children is difficult because of the multiple sex, age, and height-specific thresholds to define elevated blood pressure (BP). Blood pressureto-height ratio (BPHR) has been used to facilitate the identification of elevated BP in children. Methods: From January to June 2017, a cross-sectional study was conducted for 830 adolescents aged 12 to 15 years in Abu Kabir city, Sharkia governorate, Egypt. Blood pressure tables from the National High Blood Pressure Education Program (NHBPEP) Working Group on High Blood Pressure in Children and Adolescents were used as our standard of comparison. Sex-specific systolic and diastolic blood pressure-to-height ratios (SBPHR and DBPHR) were calculated. Receiver operating Characteristic (ROC) curve analyses were performed to assess the accuracy of BPHR for discriminating between hypertensive and non-hypertensive adolescents. Results: The prevalence of prehypertension and hypertension were 8.4% and 4.9% respectively. Optimal SBPHR and DBPHR thresholds for defining elevated BP were 0.741 and 0.475 in males, respectively, and 0.750 and 0.494 in females, respectively. The sensitivity of SBPHR and DBPHR in both sexes was all above 93%, and specificity in both sexes was above 94%. Positive predictive value for SBPHR and DBPHR was 76.4% for both in males; and 71.4% and 71.6% in females respectively; negative predictive values in both sexes were all above 98%. Conclusions: BPHR is a simple screening tool with high sensitivity and specificity for screening hypertension in adolescents.
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