Epidemiologic factors associated with mortality among hospitalized adult patients with COVID-19 in the state of Jalisco, Mexico

BACKGROUND: The SARS-CoV-2 outbreak is a significant challenge to the healthcare system in Mexico;some regions are already struggling to fight the virus. OBJECTIVE: To identify comorbidities of adult patients with COVID-19 treated in hospitals in Jalisco and to assess their associations with the risk of death. MATERIALS AND METHODS: An observational, analytical, retrospective study in which we obtained data of confirmed COVID-19 cases and their characteristics from epidemiological surveillance system of the Mexican Health Secretary through Feb 27, 2020 to November 30, 2020. RESULTS: We included 5590 patients with a mean age of 58 years, 62% were men;overall mortality was 38%. The most common concomitant conditions were hypertension, diabetes and obesity. The multivariate analysis found that chronic kidney disease (OR = 2.71), obesity (OR = 1.24), chronic obstructive pulmonary disease (OR = 1.21), diabetes mellitus (OR = 1.15) and hypertension (OR = 1.13) were independent risk factors associated with mortality. CONCLUSIONS: The risk of dying was clearly higher in individuals with comorbidities, particularly among people with chronic kidney disease or obesity.