COVID-19感染患者急性动脉和静脉血栓形成

Q4 Medicine Revista Mexicana de Angiologia Pub Date : 2021-06-25 DOI:10.24875/rma.21000017
Ana K. Trujillo-Araujo, Alfonso Cossío-Zazueta, V. M. Camarillo-Nava, Roberto C. Serrato-Auld
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引用次数: 0

摘要

背景:COVID-19感染患者存在公认的并发症,血栓形成过程与感染密切相关。目的:描述与COVID-19血栓形成事件风险增加相关的因素。材料和方法:病例对照研究确定与COVID-19患者血栓形成过程相关的因素。采用描述性统计、比较统计和推理统计以及逻辑回归。以p <0.05为差异有统计学意义,采用IBM SPSS V.25统计程序。结果:确诊急性血栓15例,其中动脉血栓17.5%,静脉血栓8.8%,男性占66.7% (n = 10)。治疗性抗凝和外科手术是必要的。出现一些共病(p = 0.005)、aPTT延长(p = 0.10)以及d -二聚体异常是一个相关的危险因素。结论:感染患者具有高凝性,血栓形成风险高。d -二聚体的显著升高可能是炎症的标志之一。出现COVID-19的情况不是任何血运重建术的禁忌症,这鼓励我们改进对COVID-19感染患者的诊断和治疗行为。
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Trombosis aguda arterial y venosa en pacientes infectados con COVID-19
Background: There are recognized complications in patients infected by COVID-19 and thrombotic processes are closely related to infection. Objective: To describe the factors associated with increased risk in thrombotic events in COVID-19. Material and methods: Case-control study to identify factors associated with thrombotic processes in patients with COVID-19. Descriptive, comparative and inferential statistics were used, as well as logistic regression. The value of p <0.05 was determined as statistically significant and the statistical program IBM SPSS V.25 was used. Results: 15 cases of acute thrombosis were as-sesed, 17.5% were arterial and 8.8% were venous, 66.7% (n = 10) were men. Therapeutic anticoagulation and surgical procedures were neccesary. There was an association as a risk factor the fact of presenting some comorbidity (p = 0.005), and prolonged aPTT (p = 0.10), as well as abnormalities in the D-dimer. Conclusions: Infected patients suffers from hypercoagulability and confers a high risk of thrombosis. Significant elevation of D-dimer may be one of the markers of inflammation. The condition of presenting COVID-19 is not a contraindication for any revascularization procedure, which encourages us to improve our diagnostic and therapeutic behavior in patients with COVID-19 infection.
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来源期刊
Revista Mexicana de Angiologia
Revista Mexicana de Angiologia Medicine-Cardiology and Cardiovascular Medicine
CiteScore
0.20
自引率
0.00%
发文量
19
审稿时长
16 weeks
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