Engaging Undergraduates in Mechanisms of Tubular Reabsorption and Secretion in the Mammalian Kidney.

If students fail to see the connections among physiological systems, they can become overwhelmed with the amount of information they need to learn. Some students have particular difficulty with the renal system for this reason. This lesson was developed to emphasize two general models in physiology that can inform student understanding of tubular reabsorption and secretion. In this two-hour lesson, students learn the mechanisms of tubular reabsorption and secretion by drawing on their prior knowledge of transport across physiological membranes (general model 1). Students also apply their knowledge of the Starling forces of capillary exchange (representing general model 2) as they learn how tubular reabsorption is regulated. The lesson is a combination of mini-lectures, used to introduce learning outcomes and more specific information, and group active learning exercises that ask students to recall prior knowledge of the two general models in physiology, make predictions, and synthesize and organize their knowledge. This lesson has fit well in a structured, upper-division physiology course. Citation: Roosa KA. 2021. Engaging undergraduates in mechanisms of tubular reabsorption and secretion in the mammalian kidney. CourseSource. https://doi.org/10.24918/cs.2021.4 Editor: Justin Shaffer, Colorado School of Mines Received: 4/5/2020; Accepted: 10/21/2020; Published: 2/20/2021 Copyright: © 2021 Roosa. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original author and source are credited. All materials are CC BY NC Kristen A. Roosa unless noted otherwise. All materials not by K. Roosa are protected by the CC BY license and the author was attributed. Conflict of Interest and Funding Statement: The author has no financial, personal, or professional conflict of interest related to this work. Supporting Materials: Supporting Files S1. Reabsorption & Secretion – Lecture Presentation Slides; S2. Reabsorption & Secretion – Activity 1; S3. Reabsorption & Secretion – Activity 1 Key; S4. Reabsorption & Secretion – Activity 2; and S5. Reabsorption & Secretion – Activity 2 Key. *Correspondence to: Biology Department, State University of New York College at Oneonta. 108 Ravine Parkway Oneonta, NY 13820. Email: Kristen.Roosa@oneonta.edu. CourseSource | www.coursesource.org 2021 | Volume 08 1 Lesson