好药,坏做法:应对伊维菌素惨败

CourseSource Pub Date : 2023-01-01 DOI:10.24918/cs.2023.17
A. Niraula, Vasudha Sundaravaradan, Rebecca M. Price
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摘要

纵观历史,生物医学的进步减轻了全世界的痛苦,显著提高了人类的福祉。作为研究人员和教育工作者,我们非常熟悉缓慢而细致的科学过程,其中一些过程最终会带来挽救生命的疗法或革命性的治愈方法。伊维菌素(Ivermectin),一种因治疗河盲症和丝虫病而享誉全球的药物,就是这样一项科学发现的壮举。然而,伊维菌素最近被错误地声称可以治疗COVID-19,危及数百万自行服用药物的人的生命。更糟糕的是,这种药物已经被武器化,以破坏疫苗,这是我们摆脱这场大流行的唯一解决方案。伊维菌素在大量人群中的流行是一个沉重的教训,说明有必要弥合科学与公众之间的差距,并将科学教育纳入我们的课程。在这节课中,学生们了解了伊维菌素如何治疗寄生虫病,但却不能治疗COVID-19,政治动机的科学错误信息如何危及人们的生命,以及缺乏对科学论文的适当监督如何加剧了伊维菌素危机。通过积极的学习技巧来培养定量技能和批判性分析,学生主导的活动和讨论,以及阅读和思考,本课程旨在使学生能够在日常生活中应用科学素养和教育。
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Good Drug, Bad Practice: Tackling the Ivermectin Fiasco
Throughout history, biomedical advancements have alleviated suffering worldwide and significantly advanced human well-being. As researchers and educators, we are well-familiar with the painstakingly slow and meticulous process of science, some of which culminates in a life-saving therapy or a revolutionary cure. Ivermectin, the drug hailed for treating river blindness and filariasis across the globe, is one such feat of scientific discovery. However, Ivermectin has lately been falsely purported to treat COVID-19, endangering the lives of millions who have taken to self-medication. Worse even, the drug has been weaponized to undermine vaccines, which are our only solution out of this pandemic. The popularity of Ivermectin among large swaths of people is a somber lesson on the need to bridge the gap between science and the public, and to incorporate science education into our curricula. In this lesson, students learn how Ivermectin treats parasitic illnesses but does not treat COVID-19, how politically-motivated scientific misinformation has jeopardized people’s lives, and how lack of proper oversight of scientific papers has fueled the Ivermectin crisis. Through active learning techniques to foster quantitative skills and critical analysis, student-driven activities and discussions, and readings and reflections, this lesson aims to empower students to apply science literacy and education in their daily lives.
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