胸椎特发性脊柱侧凸:建立表面形貌的诊断准确性和参考值

I. J. Navarro, Jessica Secrieru, C. Candotti
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摘要

研究设计:这是一项关于诊断准确性的横断面前瞻性研究。目的:建立表面形貌参数的诊断精度和分界点。方法:选取年龄在7 ~ 18岁的男女共77名。每个参与者使用两个随机选择的连续程序进行评估,通过表面形貌扫描仪和脊柱侧弯计®。本研究以脊柱侧弯测量仪(Scoliometer®)测定的躯干旋转角(ATR)为参考。为了统计目的,进行了多元线性回归分析,以确定哪些表面形貌参数具有最高的标准化β系数(β)。根据β值,选择曲线顶点和主干旋转两个地形参数组成受试者工作特征(ROC)分析。结果:地形参数的截断点为:无侧凸受试者的ATR <5°,重度侧凸受试者的ATR≥8°。曲线顶点的ROC曲线分析具有显著性(p<0.001),无侧凸受试者的曲线下面积(AUC)为76%(截断点4.4 mm),严重侧凸受试者的AUC为84%(截断点9.4 mm)。对于躯干旋转参数,AUC也很显著,无侧凸受试者的AUC为68%[截断点1.5°,p=0.023],严重侧凸受试者的AUC为73%[截断点4.8°,p=0.018]。结论:表面形貌提供了足够的准确性,可用于评估胸椎特发性脊柱侧凸的存在。
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Thoracic Idiopathic Scoliosis: Establishing the Diagnostic Accuracy and Reference Values of Surface Topography
Study design: This is a cross-sectional prospective study of diagnostic accuracy. Objective: The aim of this study was to establish the diagnostic accuracy and cut-off points of the surface topography parameters. Methods: Seventy-seven participants of both genders, aged between 7 and 18 years old, were consecutively included. Each participant was evaluated using two randomly-chosen consecutive procedures, by means of a surface topography scanner and a Scoliometer®. In this study, the angle of trunk rotation (ATR) determined using the Scoliometer® was taken as reference. For statistical purposes, a multiple linear regression analysis was made to establish which surface topography parameters have the highest standardized beta coefficients (β). Based on the β values, two topographic parameters were chosen (apex of the curve and trunk rotation) to compose the Receiver Operating Characteristic (ROC) analysis. Results: The cut-off points for the topographic parameters were established as ATR <5° for subjects without scoliosis and ≥8° for severe scoliosis. The ROC curve analysis for the apex of the curve was significant (p<0.001) with an area under the curve (AUC) ranging between 76% [cut-off point 4.4 mm] for the subjects without scoliosis and 84% [cut-off point 9.4 mm] for the subjects with severe scoliosis. For the trunk rotation parameter, the AUC was also significant, ranging between 68% [cut-off point 1.5°, p=0.023] for subjects without scoliosis, and 73% [cut-off point 4.8°, p=0.018] for the subjects with severe scoliosis.   Conclusion: Surface topography provides adequate accuracy and can be used to evaluate the presence of the thoracic idiopathic scoliosis.
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