细菌性脑膜炎继发的感染性(真菌性)颅内动脉瘤破裂1例报告及文献复习

Supreeth N Gowda
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摘要

霉菌性动脉瘤(MA)是一种罕见的全身感染并发症,是动脉壁退化和扩张的结果。病因可能是由于血管内感染性栓塞的播散(如感染性心内膜炎、菌血症)或血管外感染的扩散(如脑膜炎、骨髓炎、眼眶蜂窝织炎)。感染性颅内动脉瘤(IIA)是非常罕见的,占所有颅内动脉瘤的一小部分。大多数IIA是由细菌或真菌感染引起的。与其他动脉瘤相比,IIA由于其快速发展和血管脆弱性增加而具有更高的破裂风险。诊断主要基于临床病史和神经血管影像学。医疗管理和血管内介入治疗可被认为是未破裂IIA的一线治疗。在并发症或血管内介入失败的情况下进行开放手术。一例疑似IIA破裂继发于细菌性脑膜炎的详细讨论与文献回顾。在诊断、处理和并发症方面提出了一些建议。
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Ruptured Infective (Mycotic) Intracranial Aneurysm Secondary to Bacterial Meningitis: A Case Report and Review of Literature
Mycotic Aneurysm (MA), a rare complication of systemic infections, is a result of degradation and dilation of the arterial wall. Etiology can be due to endovascular seeding of infective emboli (e.g. infective endocarditis, bacteremia) or extravascular spread of infection (e.g. meningitis, osteomyelitis, orbital cellulitis). Infective Intracranial Aneurysms (IIA) is extremely rare and account for a small fraction of all intracranial aneurysms. Most IIA are caused by bacterial or fungal infections. IIA has a higher risk of rupture as compared to other aneurysms due to their rapid progression and increased vessel fragility. Diagnosis is mostly based on clinical history and neurovascular imaging. Medical management and endovascular intervention can be considered the first-line treatment for unruptured IIA. Open surgery is done in cases of complications or failed endovascular intervention. A case of suspected ruptured IIA secondary to bacterial meningitis is discussed in detail along with a review of the literature. Certain proposals on diagnosis, management, and complication have been put forth.
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