进行临床试验的伦理考虑综述

Shahriar Mousavinejad, S. Bazmi, M. Rezaei-Tavirani, Ehsan Shamsi-Gooshki, Seyed Ali Enjoo, M. Kiani
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引用次数: 0

摘要

临床试验被称为人体医学研究的金钥匙。因此,它们一直被这一领域的研究人员和科学家认为是有趣的话题。另一方面,由于“人类参与者”,它们需要非常小心地执行。在本文中,我们从研究设计和问题-提案审查、批准-监督、实施和结果发表四个阶段考察了这些研究的伦理必要性和考虑因素。我们使用2010年至2019年发表的文章来处理这些问题,我们发现了非常重要和突出的问题,甚至被忽视的案例。在本研究中,研究设计和问题阶段是讨论最多和挑战最大的阶段,作者对这两个阶段的敏感性一直高于其他三个阶段。另一方面,文章中引用文献数量最少的结果发表阶段被认为不太敏感。在研究过程中,我们发现研究设计是讨论最多、挑战最大的阶段,作者对其的敏感度也高于其他三个阶段。另一方面,文章中引用文献数量最少的结果发表阶段被认为不太敏感。
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A review of Ethical Considerations in Conducting Clinical Trials
Clinical trials are known as the golden key in medical science researches with human participants. Therefore, they have always been considered interesting topics by researchers and scientists working in this field. On the other hand, due to the “human participants”, they need to be performed very carefully. In this article, we have examined the ethical necessities and considerations in these researches in four stages: Research Design and Question-proposal review , approval - Supervision, implementation and publication of the results We have dealt with them using articles published between 2010 and 2019, and we have identified significantly important and prominent issues or even neglected cases. During this study, it was found that the Research Design and Question stage were the most discussed and challenged stages and the authors' sensitivity about them has been more than the other three stages. On the other hand, the results publishing stage with the least number of references in articles has been considered less sensitive. During this study, it was found that the Research Design was the most discussed and challenged stages and the authors' sensitivity about them has been more than the other three stages. On the other hand, the results publishing stage with the least number of references in articles has been considered less sensitive.
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来源期刊
CiteScore
0.60
自引率
0.00%
发文量
50
审稿时长
12 weeks
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