{"title":"转移性胰腺癌CHEK2突变携带者接受铂基治疗的完全缓解——一例报告和文献综述","authors":"Kai Sun, H. Sarfraz, M. Abdelrahim","doi":"10.31488/bjg.1000121","DOIUrl":null,"url":null,"abstract":"A 53-year-old woman presented with abdominal pain and obstructive jaundice and was diagnosed with metastatic pancreatic adenocarcinoma. She received FOLFIRINOX chemotherapy and achieved complete response. Germline testing detected CHEK2 and treatment was switched to Olaparib maintenance.","PeriodicalId":72465,"journal":{"name":"British journal of gastroenterology","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Complete Response of Metastatic Pancreatic Cancer In A CHEK2 Mutation Carrier Treated With Platinum-Based Therapy- A Case Report And Literature Review\",\"authors\":\"Kai Sun, H. Sarfraz, M. Abdelrahim\",\"doi\":\"10.31488/bjg.1000121\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"A 53-year-old woman presented with abdominal pain and obstructive jaundice and was diagnosed with metastatic pancreatic adenocarcinoma. She received FOLFIRINOX chemotherapy and achieved complete response. Germline testing detected CHEK2 and treatment was switched to Olaparib maintenance.\",\"PeriodicalId\":72465,\"journal\":{\"name\":\"British journal of gastroenterology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2020-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"British journal of gastroenterology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.31488/bjg.1000121\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"British journal of gastroenterology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.31488/bjg.1000121","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Complete Response of Metastatic Pancreatic Cancer In A CHEK2 Mutation Carrier Treated With Platinum-Based Therapy- A Case Report And Literature Review
A 53-year-old woman presented with abdominal pain and obstructive jaundice and was diagnosed with metastatic pancreatic adenocarcinoma. She received FOLFIRINOX chemotherapy and achieved complete response. Germline testing detected CHEK2 and treatment was switched to Olaparib maintenance.
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