亚低温对急性脑卒中患者康复的影响

Q4 Medicine pzshkhy blyny bn syn Pub Date : 2019-06-15 DOI:10.29252/AJCM.26.1.26
A. Rozbahani, M. Rezaee, M. Khazaei
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引用次数: 0

摘要

背景与目的:近二十年来,低温诱导已被提出用于改善脑卒中患者的恢复过程。因此,本研究的目的是探讨亚低温对急性脑卒中患者康复的影响。材料与方法:该单盲随机临床试验于2018年在伊朗哈马丹对60例急性脑卒中患者进行了研究。采用有效的抽样方法,将患者随机分为干预组和对照组。在患者头部应用冷却装置诱导轻度低温72小时。采用美国国立卫生研究院卒中量表(NIHSS)收集数据。干预后,对两组结果进行比较。最后,使用SPSS (version 22)软件对数据进行分析。结果:对照组干预前后平均得分差异无统计学意义(P < 0.05)。干预组与对照组干预前平均评分差异无统计学意义(P < 0.05)。但结果显示,干预组干预前后平均评分差异有统计学意义(P<0.05)。因此,干预组诱导低温后NIHSS平均评分明显降低。最后,干预组与对照组干预后差异有统计学意义(P<0.05)。结论:本研究结果表明,无创低温治疗急性脑卒中具有显著的临床效果。因此,可以认为,使用低温可以提高急性脑卒中患者的意识水平,降低死亡风险。因此,这种干预被认为是急性脑卒中的主要治疗方法。
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Impact of Mild Hypothermia on the Recovery of Patients with Acute Stroke
Background and Objective: Hypothermia induction has been proposed to improve the recovery process of stroke in the last two decades. Therefore, the aim of this study was to investigate the effect of mild hypothermia on the recovery of patients with acute stroke. Materials and Methods: This single-blind randomized clinical trial was conducted on 60 patients with acute stroke in 2018 in Hamadan, Iran. The patients were selected by available sampling method, and then randomly assigned into two equal-sized groups of intervention and control. Mild hypothermia was induced using a cooling device applied on the patients' head for a period of 72 h. The National Institutes of Health Stroke Scale (NIHSS) was used to collect the data. The results of both groups were compared with each other following the intervention. Finally, the data were analyzed using SPSS software (version 22). Results: The results showed no significant difference between the mean scores obtained before and after the intervention in the control group (P>0.05). In addition, there was no significant difference between the intervention and control groups in terms of the pre-intervention mean scores (P>0.05). However, the results revealed a statistically significant difference in the mean preand post-intervention scores of the intervention group (P<0.05). In this regard, the mean score of NIHSS was significantly reduced in the intervention group after the induction of hypothermia. Finally, the results were indicative of a statistically significant difference between the intervention and control groups after the intervention (P<0.05). Conclusion: As the findings of the present study indicated, noninvasively induced hypothermia has a significant clinical effect on acute stroke. Therefore, it can be argued that the use of hypothermia leads to the enhancement of consciousness level and reduction of mortality risk in patients with acute stroke. Consequently, this intervention is suggested to be considered the main therapeutic approach of acute stroke.
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来源期刊
CiteScore
0.30
自引率
0.00%
发文量
16
审稿时长
8 weeks
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