Serum Anti-Mullerian Hormone Profile from 10 Days of Age to Puberty and Its Relationship with Serum Testosterone and Estradiol Concentrations in Beetal Goat Kids

Received: Revised: Accepted: Published online: December 4, 2019 March 09, 2020 March 18, 2020 May 04, 2020 The current study aimed to define the serum profile of anti-mullerian hormone (AMH), testosterone and estradiol (E2) concentrations in Beetal goat kids from 10 days of age to puberty (175±12.6 days). The study was conducted from July 2018 to January 2019. Blood samples were collected from male kids (n=26) at 10 days interval from 10 days of age to puberty for measurement of AMH, testosterone and E2 concentrations. The body weight of all kids was measured at 10 days of age and then on monthly basis till puberty. The results showed that the mean body weight at 10 d after birth was 7.04±0.86 kg, and significantly increased till the onset of puberty (36.4±4.49 kg). The minimal plasma AMH concentration was seen at 10 d, gradually increased to its peak level (P<0.05) at 40 d and 100 d and then declined steadily till puberty. The serum testosterone level increased non-significantly from day 10 to day 50 and then gradually increased to its peak level at 170 and 180d (P<0.05). The serum E2 concentration was low at 10 days of age (5.76±0.78 pg/ml), increased to its peak level at 60d (74.3±6.26 pg/ml; P<0.05 compared with 10d), then declined till puberty. The serum AMH at early pre-pubertal age (40, 50, 70 and 80d) was positively correlated with pubertal age around 180d (r=0.99, 0.95, 0.99 and 0.94), whereas testosterone concentration was negatively correlated with serum AMH level at 60d, while positively correlated at 150 and 180d. In conclusion, goat kids exhibit a characteristic serum AMH profile along with testosterone and E2 during pre-pubertal life, such that serum AMH at an early pre-pubertal age could be used as a biomarker for predicting initiation of sexual behavior and onset of puberty. ©2020 PVJ. All rights reserved