Applications of gravitational search algorithm in parameters estimation of penicillin fermentation process model

Concerning the identification of the accurate model parameters of biological fermentation process, a parameters estimation method for non-structural dynamical model of penicillin fermentation using the Gravitational Search Algorithm( GSA) was proposed. Based on the rule of fermentation mechanism, the appropriate state equations of non-structural dynamical model were chosen; and through virtue of the global searching ability of GSA, the parameters of state equation were estimated and the accurate fermentation model was obtained. The simulation results show that GSA accurately estimated model parameters in penicillin fermentation process, the accuracy of the obtained model can meet the requirements of state estimation and condition control in penicillin fermentation process. Therefore, GSA can be applied to model parameters estimation effectively.