在Covid-19大流行期间节省有限的资源

IF 1.1 Q4 MEDICINE, RESEARCH & EXPERIMENTAL Translational Medicine at UniSa Pub Date : 2020-09-01 DOI:10.37825/2239-9747.1003
Ornella Piazza
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This problem has been aggravated by COVID19, and it is now known and feared by the large audience. If maximizing the number of saved lives is the common societal objective, and when epidemiological and clinical data support the risk of failure, can age lawfully be used for the allocation of a valuable resource as a mechanic ventilator? Simplifying, if there is an equal need between two patients, age can be the decisive element in defining the priority of treatment: lifesaving procedures, such as intubating and ventilating, will be carried out only in younger patients, reserving only less invasive or palliative treatments for the elderly. Following this principle, the elderly, lesser valued citizens, would give young people the right to play their game of life, as defined by the principle of “fair innings”, or fair life expectancy. Is the age of patients the right choice when it is selected as a triage criterion? In my opinion, age must never be the main factor that determines a person's right to intensive care, since it is an unreliable and insufficient index of the patient's ability to respond to intensive care and to recover autonomy functional. A healthy 75-year-old cannot be denied access to resuscitation treatment on the basis of age alone, although elderly patients with severe respiratory insufficiency secondary to COVID-19 have a high probability of dying despite intensive care and, consequently, they may have a lower priority for admission to intensive care in conditions of irremediable and extreme shortage of beds. The Italian Society of Anesthesia (SIAARTI) has published a document entitled \"clinical ethics recommendations for the breakdown of intensive care treatments, in exceptional circumstances limited to resources\" in partial agreement with Professor Caplan. In this document, the principle of \"saving limited resources, which can become extremely scarce, for those who have a much greater chance of survival and life expectancy, in order to maximize the benefits for the greatest number of people\" is stated. COVID 19 acute respiratory disease in frail elderly patients has a long course, and outcomes are more malignant than in healthy young subjects. SIAARTI, therefore, suggested that: \"together with the age, comorbidity and functional status of each patient in critical conditions must be carefully evaluated in these exceptional circumstances\". The British guidelines of the National Institute of Health and Care Excellence (NICE), updated to the 29 th of April 2020, suggest reserving intensive care only for patients over 65 with a low fragility score, while considering very selectively hospitalization in ICU for over sixty-five frail patients. A score greater than 5 on the Clinical Frailty Scale (CFS) should discourage attempting invasive approaches or \"wasting\" a mechanical ventilator for a patient who needs assistance for climbing stairs, washing or dressing. In this pandemic, the ethical obligation to prioritize the well-being of individual patients could be surmounted by public health policies that push to do the greater good for the largest number of patients. White and Lo [2] support the approach of giving priority to critically ill patients who are more likely to survive at discharge too. Defining a rigid cut-off a precise threshold of age and CFS score are, in my opinion, more \"defensive\" tools for young and inexperienced doctors, left in distress in the emergency room devastated by the epidemic, rather than elements of ethics to reflect on. Again, I repeat that it is essential that these decisions are based on clinical factors related to therapeutic outcomes and not on the basis of discriminatory judgments about the value of individual lives. Likewise, a simplistic age-based or disability-based withdrawal system would not only be unethical, but also illegal, since it would constitute a discrimination. These decisions are extremely distressing for both those affected and those forced to make them. Professor Aldo Masullo, a great philosopher, who died a few days ago at the age of 97, wrote about the COVID SAVING LIMITED RESOURCES DURING COVID-19 PANDEMIC","PeriodicalId":54170,"journal":{"name":"Translational Medicine at UniSa","volume":null,"pages":null},"PeriodicalIF":1.1000,"publicationDate":"2020-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":"{\"title\":\"Saving Limited Resources During Covid-19 Pandemic\",\"authors\":\"Ornella Piazza\",\"doi\":\"10.37825/2239-9747.1003\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"\\\"Age (is) an important factor in making the terrible choice of who will receive scarce resources in a pandemic.\\\", wrote Professor Arthur Caplan, Director of the section of Medical Ethics at the New York UniversityGrossman School of Medicine [1]. 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Simplifying, if there is an equal need between two patients, age can be the decisive element in defining the priority of treatment: lifesaving procedures, such as intubating and ventilating, will be carried out only in younger patients, reserving only less invasive or palliative treatments for the elderly. Following this principle, the elderly, lesser valued citizens, would give young people the right to play their game of life, as defined by the principle of “fair innings”, or fair life expectancy. Is the age of patients the right choice when it is selected as a triage criterion? In my opinion, age must never be the main factor that determines a person's right to intensive care, since it is an unreliable and insufficient index of the patient's ability to respond to intensive care and to recover autonomy functional. A healthy 75-year-old cannot be denied access to resuscitation treatment on the basis of age alone, although elderly patients with severe respiratory insufficiency secondary to COVID-19 have a high probability of dying despite intensive care and, consequently, they may have a lower priority for admission to intensive care in conditions of irremediable and extreme shortage of beds. The Italian Society of Anesthesia (SIAARTI) has published a document entitled \\\"clinical ethics recommendations for the breakdown of intensive care treatments, in exceptional circumstances limited to resources\\\" in partial agreement with Professor Caplan. In this document, the principle of \\\"saving limited resources, which can become extremely scarce, for those who have a much greater chance of survival and life expectancy, in order to maximize the benefits for the greatest number of people\\\" is stated. COVID 19 acute respiratory disease in frail elderly patients has a long course, and outcomes are more malignant than in healthy young subjects. SIAARTI, therefore, suggested that: \\\"together with the age, comorbidity and functional status of each patient in critical conditions must be carefully evaluated in these exceptional circumstances\\\". The British guidelines of the National Institute of Health and Care Excellence (NICE), updated to the 29 th of April 2020, suggest reserving intensive care only for patients over 65 with a low fragility score, while considering very selectively hospitalization in ICU for over sixty-five frail patients. A score greater than 5 on the Clinical Frailty Scale (CFS) should discourage attempting invasive approaches or \\\"wasting\\\" a mechanical ventilator for a patient who needs assistance for climbing stairs, washing or dressing. In this pandemic, the ethical obligation to prioritize the well-being of individual patients could be surmounted by public health policies that push to do the greater good for the largest number of patients. White and Lo [2] support the approach of giving priority to critically ill patients who are more likely to survive at discharge too. Defining a rigid cut-off a precise threshold of age and CFS score are, in my opinion, more \\\"defensive\\\" tools for young and inexperienced doctors, left in distress in the emergency room devastated by the epidemic, rather than elements of ethics to reflect on. Again, I repeat that it is essential that these decisions are based on clinical factors related to therapeutic outcomes and not on the basis of discriminatory judgments about the value of individual lives. Likewise, a simplistic age-based or disability-based withdrawal system would not only be unethical, but also illegal, since it would constitute a discrimination. 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引用次数: 2

摘要

纽约大学格罗斯曼医学院医学伦理部主任亚瑟·卡普兰教授写道:“在做出流行病期间谁将获得稀缺资源的糟糕选择时,年龄是一个重要因素。”这一意见,如果从其背景推断出来,将立即被任何人,无论是医务人员还是非专业人士,无论是年轻人还是老年人,视为不人道和不可接受而予以拒绝。然而,在意大利,sars -2大流行的特点是严重缺乏个人防护装备(PPE)、机械呼吸机、医院病床,特别是ICU病床,这导致不可避免地选择患者。在大流行之前,当急诊室的需求超过该地区的床位和机械呼吸机的可用性时,ICU医生往往自己面临这种情况。这一问题因covid - 19而加剧,现在为广大观众所知和恐惧。如果最大限度地挽救生命是共同的社会目标,并且当流行病学和临床数据支持失败的风险时,是否可以合法地使用年龄来分配作为机械呼吸机的宝贵资源?简单地说,如果两个病人之间有同样的需要,年龄可以成为确定治疗优先次序的决定性因素:只有年轻病人才会进行插管和呼吸等挽救生命的程序,而对老年人只保留侵入性较小或姑息性较低的治疗。遵循这一原则,老年人,较不受重视的公民,将给予年轻人玩他们的生活游戏的权利,这是由“公平回合”原则定义的,或公平的预期寿命。患者的年龄作为分诊标准是正确的选择吗?在我看来,年龄绝不能成为决定一个人是否有权接受重症监护的主要因素,因为它是病人对重症监护作出反应和恢复自主功能的能力的一个不可靠和不充分的指标。健康的75岁老人不能仅仅因为年龄而被拒绝接受复苏治疗,尽管继发于COVID-19的严重呼吸功能不全的老年患者即使接受重症监护也有很高的死亡可能性,因此,在床位极度短缺且无法补救的情况下,他们接受重症监护的优先级可能较低。意大利麻醉学会(SIAARTI)发表了一份题为“在资源有限的特殊情况下,重症监护治疗中断的临床伦理建议”的文件,部分同意卡普兰教授的意见。在这份文件中,“为那些有更大的生存机会和预期寿命的人节省有限的资源,这些资源可能变得极其稀缺,以便为最大多数人带来最大的利益”的原则得到了阐述。老年体弱患者急性呼吸道疾病病程长,预后较健康青年患者恶性。因此,SIAARTI建议:“在这些特殊情况下,必须仔细评估每位危重患者的年龄、合并症和功能状态”。英国国家健康与护理卓越研究所(NICE)的指南更新至2020年4月29日,建议仅为65岁以上、脆弱性评分低的患者保留重症监护,同时考虑对65岁以上的体弱患者非常有选择性地在ICU住院。临床虚弱量表(CFS)得分超过5分,应劝阻尝试侵入性方法或“浪费”机械呼吸机,以帮助需要帮助的患者爬楼梯,洗涤或穿衣。在这次大流行中,公共卫生政策可以超越优先考虑个别患者福祉的道德义务,推动为最多的患者提供更大的利益。White和Lo b[2]支持优先考虑重症患者的方法,这些患者在出院时也更有可能存活下来。在我看来,定义一个严格的界限,一个精确的年龄门槛和慢性疲劳综合症评分,对年轻和缺乏经验的医生来说,更多的是“防御”工具,而不是道德因素,这些医生被疫情摧毁,留在急诊室里痛苦不堪。我再次重申,这些决定必须基于与治疗结果相关的临床因素,而不是基于对个人生命价值的歧视性判断。同样,一个简单的基于年龄或残疾的退出制度不仅是不道德的,而且是非法的,因为它将构成歧视。这些决定对那些受影响的人和被迫做出决定的人来说都是极其痛苦的。几天前去世的97岁的伟大哲学家阿尔多·马苏洛(Aldo Masullo)教授写了一篇关于“COVID-19在COVID-19大流行期间节省有限资源”的文章
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Saving Limited Resources During Covid-19 Pandemic
"Age (is) an important factor in making the terrible choice of who will receive scarce resources in a pandemic.", wrote Professor Arthur Caplan, Director of the section of Medical Ethics at the New York UniversityGrossman School of Medicine [1]. This opinion, if extrapolated from its context, would be immediately rejected as inhuman and unacceptable by anyone, medical or lay people, young or old. However, in Italy, the SARSCoV-2 pandemic was marked by the severe lack of personal protective equipment (PPE), mechanical ventilators, hospital beds and in particular ICU beds, and this resulted in an inevitable selection of patients. ICU physicians, often by themselves, face this situation, when ER request exceeds the availability of beds and mechanical ventilators in the area, also before the pandemic. This problem has been aggravated by COVID19, and it is now known and feared by the large audience. If maximizing the number of saved lives is the common societal objective, and when epidemiological and clinical data support the risk of failure, can age lawfully be used for the allocation of a valuable resource as a mechanic ventilator? Simplifying, if there is an equal need between two patients, age can be the decisive element in defining the priority of treatment: lifesaving procedures, such as intubating and ventilating, will be carried out only in younger patients, reserving only less invasive or palliative treatments for the elderly. Following this principle, the elderly, lesser valued citizens, would give young people the right to play their game of life, as defined by the principle of “fair innings”, or fair life expectancy. Is the age of patients the right choice when it is selected as a triage criterion? In my opinion, age must never be the main factor that determines a person's right to intensive care, since it is an unreliable and insufficient index of the patient's ability to respond to intensive care and to recover autonomy functional. A healthy 75-year-old cannot be denied access to resuscitation treatment on the basis of age alone, although elderly patients with severe respiratory insufficiency secondary to COVID-19 have a high probability of dying despite intensive care and, consequently, they may have a lower priority for admission to intensive care in conditions of irremediable and extreme shortage of beds. The Italian Society of Anesthesia (SIAARTI) has published a document entitled "clinical ethics recommendations for the breakdown of intensive care treatments, in exceptional circumstances limited to resources" in partial agreement with Professor Caplan. In this document, the principle of "saving limited resources, which can become extremely scarce, for those who have a much greater chance of survival and life expectancy, in order to maximize the benefits for the greatest number of people" is stated. COVID 19 acute respiratory disease in frail elderly patients has a long course, and outcomes are more malignant than in healthy young subjects. SIAARTI, therefore, suggested that: "together with the age, comorbidity and functional status of each patient in critical conditions must be carefully evaluated in these exceptional circumstances". The British guidelines of the National Institute of Health and Care Excellence (NICE), updated to the 29 th of April 2020, suggest reserving intensive care only for patients over 65 with a low fragility score, while considering very selectively hospitalization in ICU for over sixty-five frail patients. A score greater than 5 on the Clinical Frailty Scale (CFS) should discourage attempting invasive approaches or "wasting" a mechanical ventilator for a patient who needs assistance for climbing stairs, washing or dressing. In this pandemic, the ethical obligation to prioritize the well-being of individual patients could be surmounted by public health policies that push to do the greater good for the largest number of patients. White and Lo [2] support the approach of giving priority to critically ill patients who are more likely to survive at discharge too. Defining a rigid cut-off a precise threshold of age and CFS score are, in my opinion, more "defensive" tools for young and inexperienced doctors, left in distress in the emergency room devastated by the epidemic, rather than elements of ethics to reflect on. Again, I repeat that it is essential that these decisions are based on clinical factors related to therapeutic outcomes and not on the basis of discriminatory judgments about the value of individual lives. Likewise, a simplistic age-based or disability-based withdrawal system would not only be unethical, but also illegal, since it would constitute a discrimination. These decisions are extremely distressing for both those affected and those forced to make them. Professor Aldo Masullo, a great philosopher, who died a few days ago at the age of 97, wrote about the COVID SAVING LIMITED RESOURCES DURING COVID-19 PANDEMIC
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Translational Medicine at UniSa MEDICINE, RESEARCH & EXPERIMENTAL-
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