MRSA菌血症和新发主动脉瓣和二尖瓣反流:一个有害和棘手的联系

IF 0.3 Q3 MEDICINE, GENERAL & INTERNAL Italian Journal of Medicine Pub Date : 2023-07-19 DOI:10.4081/itjm.2023.1618
M. Cinquegrani, F. Cei, M. Pistoia, N. Mumoli
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引用次数: 0

摘要

耐甲氧西林金黄色葡萄球菌(MRSA)菌血症是一种复杂而致命的疾病。我们报告了一名58岁女性因创伤和败血症住院3个月后出现MRSA菌血症的临床病例。在新发反流的情况下,由于利奈唑胺和万古霉素的次优治疗的应用,导致主动脉和二尖瓣心内膜炎的诊断延迟,导致疾病广泛传播并发展为脓毒性梗死。临床医生必须意识到有必要将新发瓣膜反流视为心内膜炎的高风险,并且有证据表明需要使用达托霉素治疗高危MRSA菌血症。
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MRSA bacteremia and new-onset aortic and mitral regurgitation: a pernicious and tricky association
Methicillin-resistant Staphylococcus Aureus (MRSA) bacteremia is a complex and lethal condition. We reported the clinical case of a 58-year-old woman who developed MRSA bacteremia after a 3-month hospitalization for trauma and sepsis. Delay in diagnosis of aortic and mitral endocarditis in the setting of new-onset regurgitations, as the application of suboptimal therapy with linezolid and vancomycin, led to widespread disease with embolic dissemination and development of septic infarctions. Clinicians must be aware of the necessity to consider as high risk of endocarditis new onset valvular regurgitations and of the evidence about the need for daptomycin in treating high-risk MRSA bacteremia.
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来源期刊
Italian Journal of Medicine
Italian Journal of Medicine MEDICINE, GENERAL & INTERNAL-
CiteScore
0.90
自引率
0.00%
发文量
3
审稿时长
10 weeks
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