经导管主动脉瓣置入术的微创精准入路与标准入路的安全性和有效性比较

I. Petrov, Z. Stankov, P. Polomski, J. Stoykova, A. Cherneva, D. Boychev, M. Bonev
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引用次数: 0

摘要

自2002年首例人类手术以来,经导管主动脉瓣植入术(TAVI)已经从未来的创新手术发展成为高风险患者的治疗选择,并有可能在不久的将来成为常规手术。由于良好的安全性,临床试验的新证据,TAVI在指南中提高了其推荐等级。TAVI频率的不断提高和所获得的经验导致了程序改进和标准化的需要。2013年至2021年间,我们的心血管中心有208名患者接受了TAVI。其中141例采用标准入路,其余67例采用简约精确入路。本文的主要重点是改善手术结果,患者的生活质量和舒适度,同时提供更好的药物经济学概况。详细描述了微创和精确的植入和血管装置闭合方案。与被认为是“黄金标准”的标准方法相比,极简和精确方法的安全性和效率得到了证明。同时,极简入路在桡动脉作为第二血管入路方面优于标准入路,可减少血管并发症和出血。微创入路的另一个优点是在快速起搏的同时在0/1位置植入经导管主动脉瓣,减少起搏器植入频率,减少瓣旁泄漏,减少住院时间。在过去的几年中,TAVI已被证明是高风险患者手术主动脉瓣置换术的替代方法,也适用于中低风险患者。为了使TAVI成为一个类似pci的过程,必须对其进行简化。这就是为什么TAVI需要简约和精确的方法,这是该程序的未来。
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Safety and efficiency of the minimalistic and precise approachfor transcatheter aortic valve implantation (TAVI) comparedto the standard one
Since the first procedure in humans in 2002, transcatheter aortic valve implantation (TAVI) has evolved from innovative procedure of the future to treatment of choice in high-risk patients with potential to become a routine procedure in the near future. Thanks to the excellent safety profile, the emerging evidence from clinical trials, TAVI has raised its class of recommendation in the guidelines. The constantly upraising frequency of TAVI and the experience gained have led to the need of procedure improvement and standardization. Between 2013 and 2021 208 patients underwent TAVI in our cardiovascular center. The standard approach was used for 141 of them and the minimalistic and precise approach for the rest 67 patients. The main focus of this manuscript is improvement of the procedure results, quality of life and comfort of the patients, while providing a better pharmacoeconomic profile.The minimalistic and precise protocol of implantation and the vascular device closure are thoroughly described. The safety and the efficiency of the minimalistic and precise approach compared to the standard one, which is considered the ”gold standard” are proven. At the same time the minimalistic approach is described as superior to the standard one in using the radial artery as second vascular approach to reduce vascular complications and bleeding. Other advantage of the minimalistic approach is the implantation of the transcatheter aortic valve in position 0/1 while using rapid pacing, to reduce the frequency of pacemaker implantation, reduction of paravalvular leak and reduction of hospital stay. TAVI has proved to be an alternative to surgical aortic valve replacement in high risk patients and in the past years also in intermediate and low risk patients. In order TAVI to become a PCI-like procedure it must be simplified. That is exactly why the minimalistic and precise approach for TAVI is needed and it is the future of the procedure.
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发文量
40
审稿时长
12 weeks
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