血管通路的类型和血液透析的有效性

Agata Cieniawa
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摘要

近年来,慢性肾脏疾病已被视为一种文明疾病。5期或4期肾功能衰竭患者需要肾脏替代治疗。90%的肾衰竭患者采用血液透析治疗。为了进行体外血液净化程序,有必要为患者建立血管通道。血液透析的效率可以根据尿素还原率和透析者的尿素清除率来确定。影响透析充分性的主要因素之一是血管通路的类型。目的:探讨血管通路类型对血液透析效果的影响。材料和方法:该研究包括2018年12月至2019年2月期间在克拉科夫大学医院透析的61例患者。该研究比较了血液透析前后的钾值、尿素去除程度和透析器的尿素清除率。结果:采用动静脉瘘进行透析效果最好;尿素还原比(URR)为0.7,Kt/V为1.7;使用Gero-trex人工血管透析的患者值最差。结论:血管通路的类型影响血液透析的效果。
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The type of vascular access and the effectiveness of haemodialysis
Introduction: Chronic kidney disease has been perceived in recent years as a disease of civilisation. Patients with stage 5 or 4 renal failure require renal replacement therapy. Ninety per cent of patients with renal failure are treated using haemodialysis. In order to perform extracorporeal blood purification procedures, it is necessary to establish a vascular access for the patient. The efficiency of haemodialysis can be determined based on the urea reduction rate and dialyser’s urea clearance. One of the main factors influencing the adequacy of dialysis is the type of vascular access. Aim of the study: To ascertain whether the type of vascular access influences the effectiveness of haemodialysis. Material and methods: The study included 61 patients dialysed at the University Hospital in Cracow in the period from December 2018 to February 2019. The study compared potassium values before and after haemodialysis, the degree of urea removal, and the urea clearance of the dialyser. Results: The best results were obtained by patients dialysed using an arteriovenous fistula; for those patients the urea reduction ratio (URR) was 0.7 and the Kt/V was 1.7; the worst values were found for patients dialysed using a Gero-trex artificial vessel. Conclusions: The type of vascular access affects the effectiveness of haemodialysis.
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