腓骨近端扩大刮除重建治疗股骨外侧髁巨细胞瘤的前瞻性研究

K. Dominic, Davis Dijoe, R. Aravind
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引用次数: 2

摘要

背景:影响股骨外侧髁的巨细胞瘤(GCT)在病灶扩大刮除后的重建中存在问题。本研究旨在分析腓骨上端倒置重建股骨外侧髁的病例结果。方法:选择2008年1月至2013年6月在我院接受治疗的影响股骨外侧髁的GCT患者。影像学检查和活检证实了诊断并计划手术。在扩大病灶刮除后,用腓骨近端和同种异体移植物重建空隙。结果采用肌肉骨骼肿瘤学会-87 (MSTS)评分进行测量并进行统计分析。结果:本前瞻性研究共纳入12例患者,平均年龄39岁。12例中有7例发生病理性骨折。经过至少2年的随访,病理性骨折组和非病理性骨折组的平均MSTS评分分别为25.85±2.47和27.60±0.54,差异无统计学意义(p = 0.155)。复发率为16.7%,反复刮除,感染8.3%。结论:腓骨近端扩大刮除重建股骨外侧髁GCT治疗似乎是一个可行的选择,具有良好的功能结果,即使是病理性骨折的病例。生物形式的重建具有重塑的长期优势,并且可以与重建结合为永久性的。
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Extended curettage and reconstruction with proximal fibula for treating giant cell tumor of lateral femoral condyle: A prospective study
Background: The giant cell tumor (GCT) affecting lateral femoral condyle poses problems in reconstruction after the ex tended curettage of the lesion. This study was aimed to analyze the results of cases in which the upper end of fibula was placed upside down to reconstruct the lateral femoral condyle. Methods: Patients with GCT affecting lateral femoral condyle, who underwent treatment at our institution from January 2008 to June 2013, were selected. Imaging and biopsy were done to confirm the diagnosis as well as to plan the surgery. After extended curettage of the lesion, the void was reconstructed with proximal fibula and allograft. The outcome was measured using Musculoskeletal Tumor Society-87 (MSTS) score and subjected to statistical analysis. Results: In this prospective study, twelve cases (mean age 39) were selected. Among the 12 cases, 7 had sustained the pathological fracture. After a minimum of 2 years of follow-up, the mean MSTS scores in cases with or without pathological fracture were 25.85 ± 2.47 and 27.60 ± 0.54, respectively, which was found statistically non-significant (p = 0.155). The recurrence rate was 16.7%, which underwent repeated curettage, and 8.3% had the infection. Conclusion: Treatment of GCT of lateral femoral condyle by extended curettage and reconstruction with proximal fibula seems to be a viable option with a good functional outcome, even in cases with pathological fractures. The biological form of reconstruction has the long term advantage of remodeling and can incorporate with the reconstruction as permanent.
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