儿童药物反应综合症诊断的复杂性

Q4 Medicine Quaderni ACP Pub Date : 2022-01-01 DOI:10.53141/qacp.2022.170-173

A. Pepe, Angelo Colucci, Lucia Nazzaro

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引用次数: 0

摘要

DRESS综合征(嗜酸性粒细胞增多和全身症状的药物反应)是一种复杂的、可能危及生命的药物引起的超敏反应。它的特点是大量的皮肤反应，伴有多器官受累，淋巴结病变，嗜酸性粒细胞增多。在这里我们描述一个病例DRESS综合征与急性肝功能衰竭在一个11岁的男孩由丙戊酸引发。我们强调在临床、记忆和实验室数据的基础上鉴别诊断的重要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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La complessità della diagnosi di una sindrome da reazione a farmaco nel bambino

DRESS syndrome (Drug Reaction with Eosinophilia and Systemic Symptoms) is a complex and potentially life-threatening drug induced hypersensitivity reaction. It is characterized by a massive skin reaction associated with multiorgan involvement, lymphadenopathy, eosinophilia. Here we describe a case of DRESS syndrome with acute liver failure in an 11-year-old boy triggered by Valproic Acid. We emphasize the importance of differential diagnosis on the basis of clinical, anamnestic and laboratory data.

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