Yu Lei, Dehua Zhang, Yang Liu, Guanghui Tian, Hongguang Ge
{"title":"基于1-((2-羟基乙氧基)甲基)-5-(苯基硫)- 1h -1,2,4-三唑-3-羧酰胺抗癌核苷的合成及x射线结构","authors":"Yu Lei, Dehua Zhang, Yang Liu, Guanghui Tian, Hongguang Ge","doi":"10.4236/JCPT.2014.43017","DOIUrl":null,"url":null,"abstract":"A pair of new anticancer nucleosides based on 1,2,4-triazole \nnucleosides and 1-((2-hydroxyethoxy) methyl)-5-(phenylthio)-1H-1,2,4-triazole-3-carboxamide \nhave been synthesized, and have given the corresponding products in excellent \nyields. Its structures and conformations were confirmed by single crystal X-ray \ndiffraction.","PeriodicalId":64440,"journal":{"name":"结晶过程及技术期刊(英文)","volume":"04 1","pages":"135-139"},"PeriodicalIF":0.0000,"publicationDate":"2014-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":"{\"title\":\"Synthesis and X-Ray Structure of New Anticancer Nucleosides Based on 1-((2-Hydroxyethoxy)methyl)-5-(phenylthio)-1H-1,2,4-triazole-3-carboxamide\",\"authors\":\"Yu Lei, Dehua Zhang, Yang Liu, Guanghui Tian, Hongguang Ge\",\"doi\":\"10.4236/JCPT.2014.43017\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"A pair of new anticancer nucleosides based on 1,2,4-triazole \\nnucleosides and 1-((2-hydroxyethoxy) methyl)-5-(phenylthio)-1H-1,2,4-triazole-3-carboxamide \\nhave been synthesized, and have given the corresponding products in excellent \\nyields. Its structures and conformations were confirmed by single crystal X-ray \\ndiffraction.\",\"PeriodicalId\":64440,\"journal\":{\"name\":\"结晶过程及技术期刊(英文)\",\"volume\":\"04 1\",\"pages\":\"135-139\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2014-06-23\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"结晶过程及技术期刊(英文)\",\"FirstCategoryId\":\"1087\",\"ListUrlMain\":\"https://doi.org/10.4236/JCPT.2014.43017\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"结晶过程及技术期刊(英文)","FirstCategoryId":"1087","ListUrlMain":"https://doi.org/10.4236/JCPT.2014.43017","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Synthesis and X-Ray Structure of New Anticancer Nucleosides Based on 1-((2-Hydroxyethoxy)methyl)-5-(phenylthio)-1H-1,2,4-triazole-3-carboxamide
A pair of new anticancer nucleosides based on 1,2,4-triazole
nucleosides and 1-((2-hydroxyethoxy) methyl)-5-(phenylthio)-1H-1,2,4-triazole-3-carboxamide
have been synthesized, and have given the corresponding products in excellent
yields. Its structures and conformations were confirmed by single crystal X-ray
diffraction.