类固醇反应性皮肤病中皮质类固醇使用模式的评价

Pravinkumar A Wahane, R. Jagtap, B. Ghongane
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引用次数: 8

摘要

背景:皮肤病占全球全科门诊会诊的2%,其中包括皮炎、湿疹、痤疮、荨麻疹、牛皮癣、皮肤过敏等疾病。皮质类固醇是治疗皮肤病最常用的处方药之一。收集医院门诊一级的药物使用数据已被证明是制定改进使用模式准则的有效工具。目的:了解某三级教学医院皮质类固醇药物的使用情况,并着重分析其不良反应。材料与方法:对皮肤科处方进行评价,了解现状。结果:756例患者中男性占56.34%,女性占43.65%。皮质类固醇是治疗湿疹最常用的处方(27.38%)。28.43%的药物出自世卫组织基本药物清单。外用糖皮质激素最为常见(86.48%)。92.72%的处方中提到了诊断,84.78%的处方中提到了外用皮质类固醇的剂量。84.78%的处方中提到了外用皮质类固醇的强度。高效外用皮质类固醇处方最多(63.72%)。共报告32例类固醇相关药物不良反应,以泼尼松龙最常见。结论:本研究报告了高效皮质类固醇的使用频率高于其他药物,并强调了皮肤科类固醇处方的合理和完整的必要性
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EVALUATION OF CORTICOSTEROID USE PATTERN IN STEROID RESPONSIVE DERMATOLOGICAL CONDITIONS
Background: Skin diseases account for 2% of the Out Patient Department based consultations in general practice worldwide, which includes diseases like, Dermatitis, Eczema, Acne, Urticaria, Psoriasis, skin allergy etc. Corticosteroids are one of the most commonly prescribed drugs in the skin diseases. Collection of data on the utilization of drugs at the hospital outpatient level has been shown to be an effective tool to constitute guidelines for improving utilization patterns. Objectives: Present study was designed to study utilization pattern of corticosteroid drugs with special emphasis on their adverse effects in a tertiary care teaching hospital. Materials and Methods: Prescriptions from department of dermatology were evaluated to know current trends. Results: Out of total 756 patients, 56.34% were male and 43.65 % were females. Corticosteroids were most commonly prescribed for Eczema (27.38%). 28.43 % of the drugs were prescribed from WHO essential drugs list. Corticosteroids were most commonly prescribed by topical route (86.48%). Diagnosis was included in 92.72 % of the prescriptions, while strength of the topical corticosteroidal was mentioned in 84.78 % of the prescriptions. Strength of the topical corticosteroidal was mentioned in 84.78 % of prescriptions. High potency topical corticosteroids were prescribed most frequently (63.72%). Total 32 steroid related adverse drug reactions were reported, Prednisolone was most commonly associated with adverse drug reactions. Conclusions: Present study reports use of High potency corticosteroids more frequently than others and emphasizes need of rational and complete prescribing of steroids in dermatology
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