肾移植术后患者的严重腹膜囊异孢子虫腹泻

S. Tewari, S. Garg, S. Garg
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摘要

贝利囊异孢子虫(C. belli)是一种机会性原生动物寄生虫。它在世界热带和亚热带地区流行。它经常出现在免疫功能低下的患者获得性免疫缺陷综合征(艾滋病)和其他免疫缺陷疾病。感染通常是由于粪便污染了食物和水。慢性严重水样腹泻发生在贝利梭菌感染的病人身上。通过在粪便样本中显示特征性卵囊来诊断大肠杆菌。常用的大便检查方法有湿盐涂片、碘涂片和改良抗酸染色。虽然贝利梭菌分布在世界各地,在发展中国家更为普遍,但在印度的报道不多。印度报告的大多数病例是人类免疫缺陷病毒(HIV)阳性患者,肾移植病例报告的病例不多。这里,一个27岁的男性肾移植后患者有严重的腹泻。病人抱怨过去一个月断断续续的水样腹泻,他已经从当地药房吃了一些药,但没有缓解。该患者HIV呈阴性,正在服用免疫抑制药物。采用直接湿法、碘法和抗酸染色对患者粪便标本进行检查。显微镜下观察到贝利梭菌卵囊的特征。病人接受了综合治疗,效果很好。
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Severe Cystoisospora belli Diarrhoea in Post Renal Transplant Patient
Cystoisospora belli (C. belli) is an opportunistic protozoal parasite. It is prevalent in tropical and subtropical areas of the world. It is frequently encountered in immunocompromised patients with Acquired Immunodeficiency Syndrome (AIDS) and other immunodeficiency illnesses. Infection usually occurs due to faecal contamination of food and water. Chronic severe watery diarrhoea occurs in C. belli infected patients. C. belli is diagnosed by demonstration of characteristic oocyst in the stool sample. The common methods used for stool examination are wet saline mount, iodine mount, and modified acid fast staining. Although C. belli is distributed worldwide and more prevalent in developing countries but not much reported from India. Most of the cases reported from India are in Human Immunodeficiency Virus (HIV)-positive patients and not many cases reported in renal transplant cases. Here, a case of 27-year old male post renal transplant patient having severe diarrhoea has been presented. Patient complaining of watery diarrhoea off and on for last one month for which he had taken some medicine from his local level but not got relieved. The patient was negative for HIV and was on immunosuppressive drugs. Stool sample of the patient examined by direct wet mount, iodine mount and acid fast staining. On microscopy characteristic oocysts of C. belli were detected. The patient was given combination treatment to which he responded well.
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审稿时长
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