Shiro Furuya, Jihua Liu, Zhongxuan Sun, Qiongshi Lu, Jason M Fletcher
{"title":"了解内部迁徙:利用遗传数据评估迁徙选择的研究说明。","authors":"Shiro Furuya, Jihua Liu, Zhongxuan Sun, Qiongshi Lu, Jason M Fletcher","doi":"10.1215/00703370-11053145","DOIUrl":null,"url":null,"abstract":"<p><p>Migration is selective, resulting in inequalities between migrants and nonmigrants. However, investigating migration selection is empirically challenging because combined pre- and post-migration data are rarely available. We propose an alternative approach to assessing internal migration selection by integrating genetic data, enabling an investigation of migration selection with cross-sectional data collected post-migration. Using data from the UK Biobank, we utilized standard tools from statistical genetics to conduct a genome-wide association study (GWAS) for migration distance. We then calculated genetic correlations to compare GWAS results for migration with those for other characteristics. Given that individual genetics are determined at conception, these analyses allow a unique exploration of the association between pre-migration characteristics and migration. Results are generally consistent with the healthy migrant literature: genetics correlated with longer migration distance are associated with higher socioeconomic status and better health. We also extended the analysis to 53 traits and found novel correlations between migration and several physical health, mental health, personality, and sociodemographic traits.</p>","PeriodicalId":48394,"journal":{"name":"Demography","volume":" ","pages":"1631-1648"},"PeriodicalIF":3.6000,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Understanding Internal Migration: A Research Note Providing an Assessment of Migration Selection With Genetic Data.\",\"authors\":\"Shiro Furuya, Jihua Liu, Zhongxuan Sun, Qiongshi Lu, Jason M Fletcher\",\"doi\":\"10.1215/00703370-11053145\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Migration is selective, resulting in inequalities between migrants and nonmigrants. However, investigating migration selection is empirically challenging because combined pre- and post-migration data are rarely available. We propose an alternative approach to assessing internal migration selection by integrating genetic data, enabling an investigation of migration selection with cross-sectional data collected post-migration. Using data from the UK Biobank, we utilized standard tools from statistical genetics to conduct a genome-wide association study (GWAS) for migration distance. We then calculated genetic correlations to compare GWAS results for migration with those for other characteristics. Given that individual genetics are determined at conception, these analyses allow a unique exploration of the association between pre-migration characteristics and migration. Results are generally consistent with the healthy migrant literature: genetics correlated with longer migration distance are associated with higher socioeconomic status and better health. We also extended the analysis to 53 traits and found novel correlations between migration and several physical health, mental health, personality, and sociodemographic traits.</p>\",\"PeriodicalId\":48394,\"journal\":{\"name\":\"Demography\",\"volume\":\" \",\"pages\":\"1631-1648\"},\"PeriodicalIF\":3.6000,\"publicationDate\":\"2023-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Demography\",\"FirstCategoryId\":\"90\",\"ListUrlMain\":\"https://doi.org/10.1215/00703370-11053145\",\"RegionNum\":1,\"RegionCategory\":\"社会学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"DEMOGRAPHY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Demography","FirstCategoryId":"90","ListUrlMain":"https://doi.org/10.1215/00703370-11053145","RegionNum":1,"RegionCategory":"社会学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"DEMOGRAPHY","Score":null,"Total":0}
Understanding Internal Migration: A Research Note Providing an Assessment of Migration Selection With Genetic Data.
Migration is selective, resulting in inequalities between migrants and nonmigrants. However, investigating migration selection is empirically challenging because combined pre- and post-migration data are rarely available. We propose an alternative approach to assessing internal migration selection by integrating genetic data, enabling an investigation of migration selection with cross-sectional data collected post-migration. Using data from the UK Biobank, we utilized standard tools from statistical genetics to conduct a genome-wide association study (GWAS) for migration distance. We then calculated genetic correlations to compare GWAS results for migration with those for other characteristics. Given that individual genetics are determined at conception, these analyses allow a unique exploration of the association between pre-migration characteristics and migration. Results are generally consistent with the healthy migrant literature: genetics correlated with longer migration distance are associated with higher socioeconomic status and better health. We also extended the analysis to 53 traits and found novel correlations between migration and several physical health, mental health, personality, and sociodemographic traits.
期刊介绍:
Since its founding in 1964, the journal Demography has mirrored the vitality, diversity, high intellectual standard and wide impact of the field on which it reports. Demography presents the highest quality original research of scholars in a broad range of disciplines, including anthropology, biology, economics, geography, history, psychology, public health, sociology, and statistics. The journal encompasses a wide variety of methodological approaches to population research. Its geographic focus is global, with articles addressing demographic matters from around the planet. Its temporal scope is broad, as represented by research that explores demographic phenomena spanning the ages from the past to the present, and reaching toward the future. Authors whose work is published in Demography benefit from the wide audience of population scientists their research will reach. Also in 2011 Demography remains the most cited journal among population studies and demographic periodicals. Published bimonthly, Demography is the flagship journal of the Population Association of America, reaching the membership of one of the largest professional demographic associations in the world.