肿瘤学中的药物基因组测试:卫生系统确定肿瘤学提供者观点的方法。

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2023-11-01 Epub Date: 2023-11-09 DOI:10.2217/pgs-2023-0164
Meghna Bhatt, Beth N Peshkin, Sadaf Kazi, Marc D Schwartz, Nadia Ashai, Sandra M Swain, D Max Smith
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引用次数: 0

摘要

目的:确定肿瘤医疗保健提供者对药物基因组学(PGx)测试的障碍和使用案例的态度,以及对开具抗癌和支持性护理药物的影响。材料和方法:设计了一份问卷,并将其分发给MedStar卫生系统的71名执业肿瘤学提供者。结果:70名符合条件的肿瘤科医生中有25名(36%)入选。88%的人知道PGx测试,72%的人认为PGx可以改善护理。在过去一个月内订购了含有PGx影响的药物的提供者中,对PGx用于抗癌(90-100%)和支持性护理药物(>75%)的兴趣很高。既往接受过PGx教育的提供者更有可能要求进行测试(比值比:7.9;95%可信区间:1.1-56;p=0.0394)。结论:肿瘤学提供者的处方实践和对PGx的兴趣表明有实施的机会。
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Pharmacogenomic testing in oncology: a health system's approach to identify oncology provider perspectives.

Aim: Identify oncology healthcare providers' attitudes toward barriers to and use cases for pharmacogenomic (PGx) testing and implications for prescribing anticancer and supportive care medications. Materials & methods: A questionnaire was designed and disseminated to 71 practicing oncology providers across the MedStar Health System. Results: 25 of 70 (36%) eligible oncology providers were included. 88% were aware of PGx testing and 72% believed PGx can improve care. Of providers who had ordered a medication with PGx implications in the past month, interest in PGx for anticancer (90-100%) and supportive care medications (>75%) was high. Providers with previous PGx education were more likely to have ordered a test (odds ratio: 7.9; 95% CI: 1.1-56; p = 0.0394). Conclusion: Oncology provider prescribing practices and interest in PGx suggest opportunities for implementation.

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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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