A型主动脉夹层的保守治疗:一例5年随访报告。

IF 0.7 Q3 MEDICINE, GENERAL & INTERNAL AME Case Reports Pub Date : 2023-10-13 eCollection Date: 2023-01-01 DOI:10.21037/acr-22-107
Simon Arvin, Khalil Ahmad, Mariann Tang, Gratien Andersen, Bjarne Linde Nørgaard
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引用次数: 0

摘要

背景:急性主动脉夹层会导致严重的疾病和死亡。A型主动脉夹层(TAAD)的首选治疗方法是紧急手术干预。然而,手术本身可能与重大风险相关,部分原因是一般的手术挑战以及固有的血液动力学和器官灌注不良影响。特别是,手术与八、九十岁老人和患有严重合并症的患者的围手术期死亡率显著相关。对于手术被认为是高风险的患者,保守治疗是一种替代方法,但该领域的病例文献仍然很少。病例描述:我们报告一例86岁女性TAAD患者,由于风险过大,心胸外科团队认为其无法手术。患者接受了广泛而积极的抗高血压方案的保守治疗,导致了平静的康复。结论:大多数TADs需要紧急手术治疗。然而,由于风险过大,合并症和老年患者通常禁止手术。本报告中的患者是独一无二的,因为保守治疗后随访时间长,并且由于持续的治疗监测而严格遵守治疗方案。重要的是要考虑支持和反对保守治疗策略的因素,重要的是,应仔细监测对这些策略的坚持,以优化患者的结果。
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Conservative treatment of type A aortic dissection: a case report with 5 years of follow-up.

Background: Acute aortic dissection causes major morbidities and mortalities. The treatment of choice for type A aortic dissection (TAAD) is emergent surgical intervention. However, surgery per se may be associated with significant risk, in part due to the general surgical challenges, and the inherent hemodynamic- and organ malperfusion effects. In particular, surgery correlates with marked perioperative mortality in octo- and nonagenarians and those with severe comorbidities. Conservative medical treatment represents an alternative approach to patients for whom surgery is deemed high-risk, but case literature in this field remains sparse.

Case description: We present a case of an 86-year-old female admitted with TAAD and deemed inoperable by the cardiothoracic surgical team due to excessive risks. The patient was treated conservatively with an extensive and aggressive antihypertensive regimen, leading to an uneventful recovery.

Conclusions: Most cases of TAADs require emergent surgery. However, surgery is often contraindicated in comorbid and older patients due to excessive risks. The patient in this report is unique due to the long follow-up after conservative treatment and the close adherence to treatment protocol due to continuous therapeutic monitoring. It is important to consider factors for and against conservative therapeutic strategies, and, importantly, adherence to such should be carefully monitored to optimize patient outcomes.

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