V. Peiró-Valgañón , A. Guardiola-Arévalo , A. López Fernández , E. Llorente Herrero , M.T. Martín Fernández-Gallardo
{"title":"多学科挑战:磷-32治疗局部晚期胰腺癌","authors":"V. Peiró-Valgañón , A. Guardiola-Arévalo , A. López Fernández , E. Llorente Herrero , M.T. Martín Fernández-Gallardo","doi":"10.1016/j.remn.2023.09.001","DOIUrl":null,"url":null,"abstract":"<div><p>Pancreatic cancer is a disease with a poor prognosis, and overall survival has improved the least in the last 40 years of all cancers.</p><p>Locally advanced pancreatic adenocarcinoma, without distant metastasis but with limiting vascular involvement, constitutes almost one third of these patients. This group is the focus of most research efforts to introduce treatments to increase surgical salvage rates and/or survival, with two main objectives: local control and prevention of systemic progression.</p><p>Intratumoural treatment with phosphorus-32 microparticles, guided by echoendoscopy and combined with standard chemotherapy may have significant and clinically relevant benefits in these patients, and therefore a valuable treatment option in a disease where there is an urgent need to develop new therapies to help improve outcomes.</p></div>","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"42 6","pages":"Pages 403-409"},"PeriodicalIF":1.6000,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Un reto multidisciplinar: tratamiento con fósforo-32 en el carcinoma de páncreas localmente avanzado\",\"authors\":\"V. Peiró-Valgañón , A. Guardiola-Arévalo , A. López Fernández , E. Llorente Herrero , M.T. Martín Fernández-Gallardo\",\"doi\":\"10.1016/j.remn.2023.09.001\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Pancreatic cancer is a disease with a poor prognosis, and overall survival has improved the least in the last 40 years of all cancers.</p><p>Locally advanced pancreatic adenocarcinoma, without distant metastasis but with limiting vascular involvement, constitutes almost one third of these patients. This group is the focus of most research efforts to introduce treatments to increase surgical salvage rates and/or survival, with two main objectives: local control and prevention of systemic progression.</p><p>Intratumoural treatment with phosphorus-32 microparticles, guided by echoendoscopy and combined with standard chemotherapy may have significant and clinically relevant benefits in these patients, and therefore a valuable treatment option in a disease where there is an urgent need to develop new therapies to help improve outcomes.</p></div>\",\"PeriodicalId\":48986,\"journal\":{\"name\":\"Revista Espanola De Medicina Nuclear E Imagen Molecular\",\"volume\":\"42 6\",\"pages\":\"Pages 403-409\"},\"PeriodicalIF\":1.6000,\"publicationDate\":\"2023-11-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Revista Espanola De Medicina Nuclear E Imagen Molecular\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2253654X23001002\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revista Espanola De Medicina Nuclear E Imagen Molecular","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2253654X23001002","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}
Un reto multidisciplinar: tratamiento con fósforo-32 en el carcinoma de páncreas localmente avanzado
Pancreatic cancer is a disease with a poor prognosis, and overall survival has improved the least in the last 40 years of all cancers.
Locally advanced pancreatic adenocarcinoma, without distant metastasis but with limiting vascular involvement, constitutes almost one third of these patients. This group is the focus of most research efforts to introduce treatments to increase surgical salvage rates and/or survival, with two main objectives: local control and prevention of systemic progression.
Intratumoural treatment with phosphorus-32 microparticles, guided by echoendoscopy and combined with standard chemotherapy may have significant and clinically relevant benefits in these patients, and therefore a valuable treatment option in a disease where there is an urgent need to develop new therapies to help improve outcomes.
期刊介绍：
The Revista Española de Medicina Nuclear e Imagen Molecular (Spanish Journal of Nuclear Medicine and Molecular Imaging), was founded in 1982, and is the official journal of the Spanish Society of Nuclear Medicine and Molecular Imaging, which has more than 700 members.
The Journal, which publishes 6 regular issues per year, has the promotion of research and continuing education in all fields of Nuclear Medicine as its main aim. For this, its principal sections are Originals, Clinical Notes, Images of Interest, and Special Collaboration articles.
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