基于国家血管登记的急性下肢缺血围手术期预后

P. Kuukasjärvi , J.-P. Salenius , the Finnvasc study group *
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引用次数: 52

摘要

目的:确定急性下肢缺血的死亡率和保肢率,并比较急性栓塞和血栓性外周动脉闭塞后的危险因素和结果。设计:回顾性、多中心临床研究。背景:芬兰24个外科。材料:芬兰国家血管登记处(FINNVASC)记录的1991年至1992年因急性下肢缺血接受治疗的509名患者。主要结果指标:严重截肢和死亡。主要结果:既往重大截肢或血管手术和吸烟被发现是急性血栓形成患者的危险因素(p<0.001)。术后总截肢率为16%。急性血栓形成患者的截肢率为26%,栓塞患者为10%(p<0.001)。总死亡率为13%,血栓形成患者为16%,栓塞患者则为11%(p=0.07),血栓栓塞切除术后大截肢的发生率高于重建术后(p=0.007)。结论:急性血栓形成患者大截肢率和死亡率较高。该组的高截肢率尤其与需要再次手术和血栓栓塞切除术而不是重建有关。
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Perioperative outcome of acute lower limb ischaemia on the basis of the national vascular registry

Objectives:

To determine the mortality and limb salvage rate in acute lower limb ischaemia and compare the risk factors and outcome after acute embolic and thrombotic peripheral arterial occlusion.

Design:

Retrospective, multicentre clinical study.

Setting:

24 Departments of Surgery in Finland.

Materials:

509 patients treated for acute lower limb ischaemia 1991–1992 as recorded in the Finnish national vascular registry (FINNVASC).

Chief outcome measures:

Major amputation and death.

Main results:

Previous major amputation or vascular surgery and smoking were found to be risk factors in patients with acute thrombosis (p < 0.001). The overall amputation rate was 16% during the postoperative period. The amputation rate in patients with acute thrombosis was 26% and in those with embolism 10% (p < 0.001). Overall mortality was 13%, in patients with thrombosis 16% and 11% in patients with embolism (p = 0.07). In a separate analysis of patients with acute thrombosis, major amputation was more common after thromboembolectomy than after reconstruction (p = 0.007).

Conclusion:

The rate of major amputations and mortality were higher in acute thrombosis. The high amputation rate in this group was particularly associated with the need for reoperations and thromboembolectomy rather than reconstruction.

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