妊娠期过敏性鼻炎的治疗

Kodo Sato
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引用次数: 11

摘要

许多妇女患有过敏性鼻炎。这种疾病通常是预先存在的,有时在怀孕期间是巧合,在怀孕期间可能会恶化、改善或保持不变。除了改善AR对患者生活质量的不利影响外,正确的治疗对于控制伴随的哮喘也很重要。如果可能的话,重要的是要强调在受孕前就诊时不服用此类药物的风险。尽管大多数治疗AR的药物很容易穿过胎盘,但有几种治疗方法可以控制妊娠期间的症状。根据病程和症状的不同,选择可能会有所不同,吸入皮质类固醇被认为是一线药物治疗。此外,第一代抗组胺药,如氯苯那敏,或第二代抗组胺剂,如西替利嗪或氯雷他定,都可以作为二线药物。作为一种替代方案,可以安全地使用鼻内色甘酸。一些白三烯受体拮抗剂和鼻腔减充血喷雾剂只能在其他方法不再有效且预期会有严格益处的情况下使用。在怀孕期间继续免疫治疗被认为是安全的。
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Treatment of allergic rhinitis during pregnancy

Many women suffer from allergic rhinitis (AR). The disease is often pre-existing and sometimes coincidental during pregnancy, and can worsen, improve, or stay the same during pregnancy. Besides ameliorating the detrimental effects of AR on the patient's quality of life, correct treatment is important for controlling concomitant asthma. If possible, it is important to highlight the risks of not taking such medications at a pre-conception visit. Although most medications for AR readily cross the placenta, there are several choices of treatment for controlling the symptoms during pregnancy. The choices may be varied depending on the disease course and symptoms, and inhaled corticosteroids are considered to be the first-line medical treatment. In addition, either a first-generation antihistamine, such as chlorpheniramine, or a second-generation antihistamine, such as cetirizine or loratadine, can be prescribed as the second-line medical treatment. As an alternative, intranasal cromolyn can be prescribed safely. Some of the leukotriene receptor antagonists and nasal decongestant sprays can only be prescribed when other methods are no longer valid and strict benefits can be expected. It is considered safe to continue immunotherapy during pregnancy.

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