原发性硬化性胆管炎的表型及鉴别诊断。

IF 2.9 3区 医学 Q2 GASTROENTEROLOGY & HEPATOLOGY Clinics in liver disease Pub Date : 2023-08-17 DOI:10.1016/j.cld.2023.07.006
Brian H. Horwich MD, MS , Douglas T. Dieterich MD
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引用次数: 0

摘要

原发性硬化性胆管炎是一种异质性免疫介导的疾病,其特征是慢性炎症和胆管狭窄。尽管驱动病理生理机制仍然难以捉摸,但有几个观察到的临床表型的疾病。胆管受累的分布、伴有炎症性肠病的存在、IgG4阳性浆细胞的显著浸润以及与其他自身免疫性疾病的重叠特征对预后和治疗具有重要意义。由于尚未发现原发性硬化性胆管炎的病理特征,广泛的鉴别诊断和对其他潜在原因的广泛评估对于适当的治疗至关重要。
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来源期刊
Clinics in liver disease
Clinics in liver disease GASTROENTEROLOGY & HEPATOLOGY-
CiteScore
5.30
自引率
0.00%
发文量
79
审稿时长
>12 weeks
期刊介绍: A perfect source to consult for those in the fields of gastroenterology and hepatology, Clinics in Liver Disease provides answers to clinical questions, information on the latest diagnostic methods and treatments, and numerous clinical images. Published quarterly—in February, May, August, and November—each issue offers in-depth reviews that focus on the liver and biliary system.
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