哥伦比亚患者的处方模式和驱虫药的使用:一项横断面研究。

IF 1 4区 医学 Q4 PARASITOLOGY Journal of Parasitology Pub Date : 2023-11-01 DOI:10.1645/22-8
Maria Camila Montes-Montoya, Andrés Gaviria-Mendoza, Maria Mónica Murillo-Muñoz, Jaime Andrés Cardona-Ospina, Jorge Enrique Machado-Alba
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引用次数: 0

摘要

肠道寄生虫仍然是中低收入国家的一个公共卫生问题。在许多地区,在驱虫计划中广泛使用驱虫剂仍然是必要的。然而,对这些药物在普通医学实践中的使用情况的描述有限。本研究的目的是确定一组哥伦比亚患者使用驱虫药物及其适应症。这是一项来自配药数据库的描述性研究,旨在确定服用驱虫药的患者。共有381例病例被随机选择,并对其医疗记录进行了审查,分析了社会人口统计学、临床和药理学变量(使用指征)。没有寄生虫的诊断登记或临床表现被确定为没有适应症的处方。总的来说,50.9%(n=194)的患者是女性,67.4%的患者年龄在18岁以下。114名(29.9%)患者明确诊断出蠕虫病,其中只有4.2%(n=16)得到微生物证实。最常用的驱虫药是阿苯达唑(占所有处方的70.4%)。266例(69.8%)没有指示使用驱虫药。营养补充剂或维生素处方与使用无指示的驱虫药有关(比值比:2.25;95%置信区间:1.26-4.03)。很大一部分患者的临床记录中缺乏支持使用驱虫药的症状或诊断。
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PRESCRIBING PATTERNS AND THE USE OF ANTHELMINTIC DRUGS IN COLOMBIAN PATIENTS: A CROSS-SECTIONAL STUDY.

Intestinal parasites continue to be a public health problem in low- and middle-income countries. Broad use of anthelmintics during deworming programs is still necessary in many regions. However, description of the usage of these medications in general medical practice has been limited. The objective of this study was to determine the use of anthelmintic drugs and their indications in a group of Colombian patients. This was a descriptive study from a drug-dispensing database, identifying patients with prescriptions for anthelmintic drugs. A total of 381 cases were randomly selected, and their medical records were reviewed, analyzing sociodemographic, clinical, and pharmacological variables (indication of use). The lack of diagnosis registration or clinical manifestations of parasites was determined as a prescription without indication. In total, 50.9% (n = 194) of patients were female, and 67.4% of all patients were under 18 yr of age. The diagnosis of helminthiases was clearly stated in 114 (29.9%) patients, and only 4.2% (n = 16) of these had microbiological confirmation. The most commonly used anthelmintic drug was albendazole (70.4% of all prescriptions). The use of anthelmintics was not indicated in 266 cases (69.8%). Nutritional supplements or vitamin prescriptions were associated with using anthelmintics without indication (odds ratio: 2.25; 95% confidence interval: 1.26-4.03). A high proportion of patients lacked symptoms or diagnoses in their clinical records that supported the use of anthelmintic drugs.

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来源期刊
Journal of Parasitology
Journal of Parasitology 医学-寄生虫学
CiteScore
2.10
自引率
7.70%
发文量
60
审稿时长
2 months
期刊介绍: The Journal of Parasitology is the official peer-reviewed journal of the American Society of Parasitologists (ASP). The journal publishes original research covering helminths, protozoa, and other parasitic organisms and serves scientific professionals in microbiology, immunology, veterinary science, pathology, and public health. Journal content includes original research articles, brief research notes, announcements of the Society, and book reviews. Articles are subdivided by topic for ease of reference and range from behavior and pathogenesis to systematics and epidemiology. The journal is published continuously online with one full volume printed at the end of each year.
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