{"title":"两次折叠","authors":"N. Viget , L. Legout , S. Alfandari","doi":"10.1016/j.emcmi.2004.09.001","DOIUrl":null,"url":null,"abstract":"<div><p>Ketolides are semi-synthetic derivatives of Erythromycin A. Telithromycin is the first introduced in clinical practice. It was developed specifically for the treatment of community-acquired respiratory tract infections, since it demonstrates bacteriological efficiency against common and atypical respiratory pathogens, as well as good diffusion in respiratory tissues. It maintains efficacy against erythromycin resistant Gram-positive cocci and seems to not induce MLS<sub>B</sub> resistance. Telithromycin is available currently, but the other agents of this therapeutic class are not marketed yet.</p></div>","PeriodicalId":100430,"journal":{"name":"EMC - Maladies Infectieuses","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2005-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.emcmi.2004.09.001","citationCount":"0","resultStr":"{\"title\":\"Kétolides\",\"authors\":\"N. Viget , L. Legout , S. Alfandari\",\"doi\":\"10.1016/j.emcmi.2004.09.001\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Ketolides are semi-synthetic derivatives of Erythromycin A. Telithromycin is the first introduced in clinical practice. It was developed specifically for the treatment of community-acquired respiratory tract infections, since it demonstrates bacteriological efficiency against common and atypical respiratory pathogens, as well as good diffusion in respiratory tissues. It maintains efficacy against erythromycin resistant Gram-positive cocci and seems to not induce MLS<sub>B</sub> resistance. Telithromycin is available currently, but the other agents of this therapeutic class are not marketed yet.</p></div>\",\"PeriodicalId\":100430,\"journal\":{\"name\":\"EMC - Maladies Infectieuses\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2005-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/j.emcmi.2004.09.001\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"EMC - Maladies Infectieuses\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1638623X04000228\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"EMC - Maladies Infectieuses","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1638623X04000228","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Ketolides are semi-synthetic derivatives of Erythromycin A. Telithromycin is the first introduced in clinical practice. It was developed specifically for the treatment of community-acquired respiratory tract infections, since it demonstrates bacteriological efficiency against common and atypical respiratory pathogens, as well as good diffusion in respiratory tissues. It maintains efficacy against erythromycin resistant Gram-positive cocci and seems to not induce MLSB resistance. Telithromycin is available currently, but the other agents of this therapeutic class are not marketed yet.
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