{"title":"剖析女性的脂质和脂蛋白问题:从子宫到更年期的旅程","authors":"T. Dayspring, S. Baum","doi":"10.2217/clp.15.28","DOIUrl":null,"url":null,"abstract":"Abstract Over the last decade, a host of sex differences have been elucidated in the realm of cardiovascular disease (CVD), including both its presentation and response to treatment. It has been suggested that the term ‘ischemic heart disease’ be used in preference to ‘coronary heart disease’ when referring to CVD in women, due to the fact that women, even when symptomatic, have lower amounts of obstructive plaque than do men. However, more than 80% of middle-aged women have one or more standard (and numerous novel) CVD risk factors. This review will focus primarily on lipid/lipoprotein biology and plasma concentrations in women, beginning in the fetus and extending through childhood, adolescence, pregnancy, midlife and postmenopausal periods.","PeriodicalId":55252,"journal":{"name":"Clinical Lipidology","volume":"12 1","pages":"431 - 448"},"PeriodicalIF":0.0000,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Dissecting lipid and lipoprotein issues in women: an in utero-through-menopause journey\",\"authors\":\"T. Dayspring, S. Baum\",\"doi\":\"10.2217/clp.15.28\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Abstract Over the last decade, a host of sex differences have been elucidated in the realm of cardiovascular disease (CVD), including both its presentation and response to treatment. It has been suggested that the term ‘ischemic heart disease’ be used in preference to ‘coronary heart disease’ when referring to CVD in women, due to the fact that women, even when symptomatic, have lower amounts of obstructive plaque than do men. However, more than 80% of middle-aged women have one or more standard (and numerous novel) CVD risk factors. This review will focus primarily on lipid/lipoprotein biology and plasma concentrations in women, beginning in the fetus and extending through childhood, adolescence, pregnancy, midlife and postmenopausal periods.\",\"PeriodicalId\":55252,\"journal\":{\"name\":\"Clinical Lipidology\",\"volume\":\"12 1\",\"pages\":\"431 - 448\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2015-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical Lipidology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.2217/clp.15.28\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Lipidology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2217/clp.15.28","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q","JCRName":"Medicine","Score":null,"Total":0}
Dissecting lipid and lipoprotein issues in women: an in utero-through-menopause journey
Abstract Over the last decade, a host of sex differences have been elucidated in the realm of cardiovascular disease (CVD), including both its presentation and response to treatment. It has been suggested that the term ‘ischemic heart disease’ be used in preference to ‘coronary heart disease’ when referring to CVD in women, due to the fact that women, even when symptomatic, have lower amounts of obstructive plaque than do men. However, more than 80% of middle-aged women have one or more standard (and numerous novel) CVD risk factors. This review will focus primarily on lipid/lipoprotein biology and plasma concentrations in women, beginning in the fetus and extending through childhood, adolescence, pregnancy, midlife and postmenopausal periods.
期刊介绍：
The Journal of Clinical Lipidology is published to support the diverse array of medical professionals who work to reduce the incidence of morbidity and mortality from dyslipidemia and associated disorders of lipid metabolism. The Journal''s readership encompasses a broad cross-section of the medical community, including cardiologists, endocrinologists, and primary care physicians, as well as those involved in the treatment of such disorders as diabetes, hypertension, and obesity. The Journal also addresses allied health professionals who treat the patient base described above, such as pharmacists, nurse practitioners and dietitians. Because the scope of clinical lipidology is broad, the topics addressed by the Journal are equally diverse. Typical articles explore lipidology as it is practiced in the treatment setting, recent developments in pharmacological research, reports of treatment and trials, case studies, the impact of lifestyle modification, and similar academic material of interest to the practitioner. While preference is given to material of immediate practical concern, the science that underpins lipidology is forwarded by expert contributors so that evidence-based approaches to reducing cardiovascular and coronary heart disease can be made immediately available to our readers. Sections of the Journal will address pioneering studies and the clinicians who conduct them, case studies, ethical standards and conduct, professional guidance such as ATP and NCEP, editorial commentary, letters from readers, National Lipid Association (NLA) news and upcoming event information, as well as abstracts from the NLA annual scientific sessions and the scientific forums held by its chapters, when appropriate.
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