仿制药替代的预测因素和医生感知替代的排他性:对医生的横断面调查

Georges Hatem, N. Navasardyan, Elsa Lahoud, S. Awada, Rana Itani, R. Ajrouche, Mathijs Goossens
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引用次数: 4

摘要

使用非专利药物有助于获得治疗并降低总体保健费用。促进仿制药替代的政策考虑到质量和功效等许多组成部分,考虑到包括医生和药剂师在内的健康利益攸关方,并确定影响仿制药处方的因素。目前的研究旨在评估医生对仿制药的看法与他们的性别和年龄之间的关系,以及他们在初始治疗后转向仿制药的意愿。此外,它旨在评估在初始治疗后将品牌转换为仿制药的预测因素,并感知执行这种替代的排他性。与50岁及以上的医生相比,年轻医生为降低医疗费用而开非专利药的情况更为普遍。有趣的是,与30岁以下的医生相比,40岁及以上的医生更倾向于给没有医疗保险的患者开非专利药。年龄与将初始治疗转为非专利药显著相关,50岁以上医生的这一比例是30岁以下医生的2.46倍。此外,执业超过20年的医生接受品牌初始治疗后由药剂师替代的比例是执业不足10年的医生的1.5倍。增加非专利替代和促进其接受的策略应考虑到不同的重要预测因素。但是,还需要进一步的研究来探索更多的因素来预测黎巴嫩的仿制药处方,如医疗代表的来访,医生所执业医院的规章制度,这些因素也被证明对仿制药的处方实践有很大的影响。
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Predictors of substitution to generic drugs and physicians’ perceived exclusivity of substitution: A cross sectional survey among physicians
The use of generic medicines facilitate access to treatment and reduce the overall health cost. Policies promoting generic substitution take into account many components such as quality and efficacy considering health stakeholders including physicians and pharmacists and identifying factors impacting generics prescription. The current study aimed to assess the association between the perception of physicians towards generics with their sex and age and their willingness to switch to generics after initial treatment. Furthermore, it aimed to evaluate the predictors for switching brands to generics after initial treatment and perceiving the exclusivity to perform this substitution. Prescription of generics to lower medical cost was more common among younger physicians compared to those 50 years and older. Interestingly, physicians aged 40 and above were more prone to prescribe generics to patients without medical coverage, while compared to physicians younger than 30 years of age. Age was significantly associated with switching initial treatment to generics, which was 2.46 times higher for physicians older than 50 years compared to those younger than 30 years. In addition, physicians practicing more than 20 years were about 1,5 times more accepting the substitution by pharmacists after initial treatment by brand while compared to physicians practicing for less than 10 years. Strategies to increase generic substitution and promoting its acceptance among physicians should take into consideration the different significant predictors. However, Further research is required to explore more factors, predicting prescription of generics in Lebanon, such as visits by medical representatives, regulations of the hospital that the physician is practicing, which are also proven to have high influence on the prescription practice of generics.
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