影响膀胱癌患者根治性膀胱切除术后康复的预后因素

Rendy Triyaka, A. Z. Hendri
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摘要

目的:了解膀胱癌患者根治性膀胱切除术后恢复时间的独立预后因素。因此在手术前和手术后的处理中要考虑病人的可行性。材料与方法:本研究是一项回顾性观察性分析研究,旨在探讨膀胱癌患者手术前变量与根治性膀胱切除术后治疗时间的关系。结果:从本研究结果可知,老年患者(65岁以上)术后平均护理时间较65岁以下患者短,平均护理时间分别为17.08天和18.03天,本分析的p值为0.781。血红蛋白、白蛋白、HALP评分较低的患者术后住院时间较长,P值分别为0.384、0.276、0.603,其中回肠导管两种手术间住院时间最长,P值为0.904。体重过轻的患者术后平均护理时间为16.5天,BMI正常的患者术后平均护理时间为19.59天。这些平均值之间的差异p值为0.396,可知老年患者(65岁以上)的平均术后护理时间较65岁以下患者短,分别为17.08天和18.03天。本分析的p值为0.781,发现血红蛋白、白蛋白、HALP评分较低的患者术后治疗时间较长,p值分别为0.384、0.276、0.603。应用ERAS方案的患者的平均术后护理时间(15.67天)比未应用ERAS方案的患者(18.16天)更快。然而,这一差异的p值为0.518。结论:本研究认为没有预后因素能独立预测膀胱癌根治性膀胱切除术后患者治疗时间。因此,在进行根治性膀胱切除术之前,需要深入评估各种因素,以达到最佳的术后恢复率。
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PROGNOSTIC FACTORS TOWARD BLADDER CANCER PATIENT RECOVERY AFTER RADICAL CYSTECTOMY SURGERY
Objective: This study aimed to know independent prognostic factors to predict the recovery time of bladder cancer patients after radical cystectomy. So that it would be a consideration to determine patient feasibility before surgery and after surgery management. Material & Methods: This study was an observational analytical study with a retrospective approach to examine the relationship between pre-surgery variables of the bladder cancer patients and the duration of treatment post radical cystectomy. Results: From the results of this study, it is known that the average length of postoperative care for older patients (above 65 years) was lower when compared to patients under 65 years with averages of 17.08 and 18.03 days respectively p-value of this analysis was 0.781. Patients with low hemoglobin, albumin, and HALP scores had longer postoperative hospitalization periods but with P values of 0.384, 0.276, and 0.603, the ileal conduit has the longest hospitalization treatment period between the two other procedures, with a P-value of 0.904. It was found that the average length of postoperative care for underweight patients was 16.5 days and for patients with normal BMI was 19.59 days. The difference between these averages showed a p-value of 0.396 it is known that the average length of postoperative care for older patients (above 65 years) was lower when compared to patients under 65 years with averages of 17.08 and 18.03 days respectively. The p-value of this analysis was 0.781 it was found that patients with low hemoglobin, albumin, and HALP scores had longer postoperative treatment periods, p-value 0.384, 0.276, and 0.603. The average duration of postoperative care for patients who applied the ERAS protocol tended to be faster (15.67 days) compared to patients who did not apply the ERAS protocol (18.16 days). Nevertheless, the p-value of this difference was 0.518. Conclusion: This study concludes that there is no prognostic factor that can independently predict the duration of treatment of bladder cancer patients post-radical cystectomy. Therefore in-depth assessment of various factors is required before performing radical cystectomy to achieve the best postoperative recovery rates.
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