长骨骨折患者尿液中的脂肪球蛋白水平

Dr. Vishanth Rai, D. Tm, Dr. Rathin Shetty
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摘要

导论:随着世界范围内创伤发生率的增加,与过去相比,全球范围内涉及长骨的骨折发生率也有所增加(1,2)。在创伤病例中,伴随复杂骨折发生的还有各种相关损伤。材料和方法:本研究是在机构研究委员会批准和人类伦理委员会批准后进行的。在获得知情的书面同意后,所有符合A.J.I.M.S.纳入和排除标准的患者将被考虑纳入研究。一旦病人适合手术,病人就由资深工作人员进行手术。术前送尿进行脂肪球蛋白检测,术后3小时内送尿进行脂肪球蛋白评价检测。采用SPSS 17.0软件对收集的数据进行分析。观察与结果:男性88% p =0.008,左侧52% p =0.078。4 ~ 5例骨折中以胫骨骨折最常见,胫腓骨合并骨折67例,占44.00%。100例患者术后尿脂球蛋白检查均为阴性。术前尿脂肪球蛋白检查阳性占2%。结论:1本研究发现,2%的长骨骨折患者存在尿脂球蛋白。两例患者均有多处骨折。在这两起病例中,向医院报告的时间都延误了4个多小时。两例患者均有BMI升高,且骨折累及长骨,与并发症无相关性。
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Urine for fat globulin levels in long bone fractures
Introduction: With the increasing incidence of trauma worldwide there has been an increase in the incidence of fractures involving the long bones globally as compared to the past (1, 2). There are a variety of associated injuries that occur along with the complex fractures in cases of trauma. Materials and Methods: The study was conducted after institutional research board clearance and after approval from the human ethics committee. All patients fulfilling the inclusion and exclusion criteria admitted at A.J.I.M.S. will be considered for the study after obtaining informed written consent. Once the patient was fit for surgery patient were operated by senior staff. Preoperatively the urine was sent for detection of fat globulin and Postoperatively the urine was sent for detection of fat globulin evaluation within 3 hours of surgery. The collected data was analysed by SPSS 17.0 version software. Observations and Results: Males were 88% p =0.008, left side 52% p =0.078. 33% were admitted within 4-5 Among all bones tibia was the commonest of the bone fracture involved 67 cases, combination of tibia and fibula was the commonest seen in 44.00%.The examination of urine for fat globulin post operatively was negative in all 100 of the cases. The examination of urine for fat globulin pre operatively was positive in 2% of the cases. Conclusion: 1 The present study we found that urine fat globulins in fractures involving the long bone are present in two percent of cases. In both cases the patients had sustained multiple bone fractures. There was a delay in presentation to the hospital of more than 4 hours in both cases. Both patients had an elevated BMI fat in urine in fractures involving the long bone have no correlation to complications.
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