改良版的炉干淀粉(黄疸,黄疸)作为药片干燥配方的试剂

Shan Amadeus, I. Putra
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引用次数: 0

摘要

辅料的物理性质对生产优质片剂非常重要。淀粉或淀粉是一种附加材料,通常用于制造片剂。对片剂有利的淀粉或粉剂的物理性质,只要质量好,就能达到预期的效果。未变性淀粉可压缩性差,易碎性大,在片剂中会发生封盖现象。芋头作为一种潜在的淀粉,由于其淀粉含量高,可作为片剂的辅料。芋头作为赋形剂需要进行物理和化学改性,以生产具有更好和更具体的药物特性的衍生物,特别是用于片剂的制造。本研究的目的是确定芋头淀粉的物理性能是否符合良好物理性能的参数。感官试验得到的芋芋淀粉呈粉末状,无气味、无味、白色;知识试验得到的芋芋淀粉经碘处理后呈深蓝色;显微试验得到的芋芋淀粉呈簇状排列,芋门位于中间,芋门呈点状、直线状。含水量试验采用9.40%干燥24小时、8.42%干燥48小时、7.9%干燥72小时的干燥柜,根据干燥时间的长短,得到各变性淀粉的含水量值。pH试验得到,干燥24小时的pH值为6.52,干燥48小时的pH值为6.22,干燥72小时的pH值为5.92。
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Uji Modifikasi Lemari Pengering Pati Talas Kimpul (Xanthosoma sagittifolium) sebagai Eksipien dalam Formulasi Tablet Terhadap Lama Pengeringan
The physical properties of excipients are very important to know for the manufacture of good tablets. Starch or amylum is an additional material that is often used in the manufacture of tablets. The physical properties of starch or powder that are good for tablets can give the desired effect if they have good quality. Unmodified starch does not have good compressibility and has great friability, and capping will occur in the tablet. Taro taro as a potential starch can be used as an excipient in the manufacture of tablets because it has a high starch content. Taro taro used as an excipient needs to be modified physically and chemically to produce derivatives that have better and more specific pharmaceutical characteristics, especially for the manufacture of tablets. The purpose of this study was to determine whether the physical properties of taro starch matched the parameters of good physical properties. Tests carried out included organoleptic tests which obtained powder like flour, had no odor, had no taste and had a white color, Knowledge test obtained dark blue in modified taro starch solution after being given iodine, Microscopic tests obtained taro starch results which had the arrangement is clustered with the hilus located in the middle, the shape of the hilus is in the form of a point, a straight line. The water content test obtained the water content value of each modified starch based on the length of drying time using a drying cabinet of 9.40% for drying for 24 hours, 8.42 % for drying for 48 hours, and 7.9% for drying for 72 hours and pH Test Produces a pH value of 6.52 for drying for 24 hours, 6.22 for drying for 48 hours and 5.92 for drying for 72 hours.
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来源期刊
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22
审稿时长
4 weeks
期刊最新文献
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