L. Basso, Mehdi Benamar, Xavier Mas-Orea, C. Deraison, C. Blanpied, N. Cenac, A. Saoudi, G. Dietrich
{"title":"IL - 10缺失小鼠中T细胞源性阿片类药物内源性控制炎性内脏疼痛","authors":"L. Basso, Mehdi Benamar, Xavier Mas-Orea, C. Deraison, C. Blanpied, N. Cenac, A. Saoudi, G. Dietrich","doi":"10.1111/nmo.13743","DOIUrl":null,"url":null,"abstract":"The opioid‐mediated analgesic activity of mucosal CD4+ T lymphocytes in colitis has been reported in immunocompetent mice so far. Here, we investigated whether CD4+ T lymphocytes alleviate from inflammation‐induced abdominal pain in mice with defective immune regulation.","PeriodicalId":19104,"journal":{"name":"Neurogastroenterology & Motility","volume":"26 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2020-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"13","resultStr":"{\"title\":\"Endogenous control of inflammatory visceral pain by T cell‐derived opioids in IL‐10‐deficient mice\",\"authors\":\"L. Basso, Mehdi Benamar, Xavier Mas-Orea, C. Deraison, C. Blanpied, N. Cenac, A. Saoudi, G. Dietrich\",\"doi\":\"10.1111/nmo.13743\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The opioid‐mediated analgesic activity of mucosal CD4+ T lymphocytes in colitis has been reported in immunocompetent mice so far. Here, we investigated whether CD4+ T lymphocytes alleviate from inflammation‐induced abdominal pain in mice with defective immune regulation.\",\"PeriodicalId\":19104,\"journal\":{\"name\":\"Neurogastroenterology & Motility\",\"volume\":\"26 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2020-02-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"13\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Neurogastroenterology & Motility\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1111/nmo.13743\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Neurogastroenterology & Motility","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1111/nmo.13743","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Endogenous control of inflammatory visceral pain by T cell‐derived opioids in IL‐10‐deficient mice
The opioid‐mediated analgesic activity of mucosal CD4+ T lymphocytes in colitis has been reported in immunocompetent mice so far. Here, we investigated whether CD4+ T lymphocytes alleviate from inflammation‐induced abdominal pain in mice with defective immune regulation.
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