阿育吠陀血液制剂与传统铁制剂对女性贫血患者的比较临床研究

J. Hannan, Prawej Ansari, H. Bakshi, M. Shahriar, S. Azam, Hakkim L. Faruck, Msk, Choudhuri
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摘要

贫血是一种常见的营养失调,影响着全球三分之一的人口。评估人的营养状况是健康生活的必然过程。与男性相比,女性更容易患贫血。根据世卫组织的报告,开发以草药为基础的配方来治疗贫血患者是安全且毒性较小的。在这项研究中,对66名年龄在20-30岁之间的女性贫血志愿者进行了阿育吠陀血液制剂Nabayas Louha (NBL)与g -铁叶酸(IFA)的双盲、跨组比较临床试验。结果显示,每天给药500毫克的NBL,连续30天显著增加了治疗志愿者的血红蛋白含量。使血清铁含量升高,总铁结合力降低。ESR水平也有所下降。发现NBL的这些影响与IFA相当。白细胞计数明显减少,但淋巴细胞计数有统计学意义的增加。此外,NBL处理组的毒性相关酶SGOT和SGPT水平没有显著改变,生动地证实了补充NBL是无毒的。综上所述,NBL可作为缺铁性贫血和白细胞紊乱的补充治疗。关键词:贫血;阿育吠陀;Haematinic;世界卫生组织(WHO);Nabayas louha (NBL);叶酸铁(IFA);红细胞沉降率;白细胞;谷丙转氨酶(GPT);血清谷草转氨酶(SGOT);血清谷丙转氨酶;总铁结合力(TIBC);缺铁性贫血(IDA)
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Comparative Clinical Study of Nabayas Louha: An Ayurvedic HaematinicPreparation and a Conventional Iron Preparation in Female Anemic Patients
Anemia is common nutritional disorder and it affects one third of population around the globe. Assessing nutritional status of human is an inevitable process to lead a healthy life. Females are affected significantly by anemia compare to male. According to WHO report, developing herbs-based formulation to treat anemic patients is safe and less toxic. In this study a double-blind, cross group comparative clinical trial of Nabayas Louha (NBL) a Ayurvedic haematinic preparation with G-Iron Folic Acid (IFA) was undertaken on 66 female anemic volunteers with age between 20-30 years. It was seen that NBL after being administered at a daily dose of 500 mg for 30 days significantly increased the hemoglobin content of the treated volunteers. It produced an increase in serum iron content and decreases total iron binding capacity. The ESR level was also decreased. These effects of NBL were found to be comparable with IFA. There was a marked decrease in WBC count noticed, however statistically significant increase in the lymphocytes count was seen. Furthermore, the level of toxicity related enzymes SGOT and SGPT was not altered significantly in the NBL treated group which vividly confirm that supplementation of NBL is not toxic. In conclusion, these findings recommend use of NBL as supplement in the treatment of iron deficiency anemia and WBC disorders Keywords: Anemia; Ayurvedic; Haematinic; Nabayas louha Abbreviations: World health organization (WHO); Nabayas louha (NBL); Iron folic acid (IFA); Erythrocyte sedimentation rate (ESR); White blood cell (WBC); Glutamic-pyruvic transaminase (GPT); serum glutamic-oxaloacetic transaminase (SGOT); Serum glutamic pyruvic transaminase (SGPT); Total iron binding capacity (TIBC); Iron deficiency anemia (IDA)
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