酵母菌的上位性与杂交不育

D. Greig, R. Borts, E. Louis, M. Travisano
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引用次数: 100

摘要

杂交不育被认为是由于来自不同物种的基因之间有害的上位性相互作用。本研究表明,显性基因不亲和性不会导致酿酒酵母与5个近缘种杂交的不育性。不育的二倍体通过基因组加倍产生杂交四倍体而获得可育性。基于这些和以前的结果,我们得出结论,无论是基因不相容还是经典的染色体物种形成模型都不适用。
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Epistasis and hybrid sterility in Saccharomyces
Hybrid sterility is thought to be due to deleterious epistatic interactions between genes from different species. Here we demonstrate that dominant genic incompatibility does not contribute to sterility in hybrids between Saccharomyces cerevisiae and five closely related species. Sterile diploids were made fertile by genome doubling to produce hybrid tetraploids. Based on these and previous results, we conclude that neither genic incompatibility nor classical chromosomal speciation models apply.
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