由本刊编辑从本刊精选的重要文章

Q2 Biochemistry, Genetics and Molecular Biology Clinical and Vaccine Immunology Pub Date : 2017-01-01 DOI:10.1128/CVI.00535-16
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引用次数: 0

摘要

人们对养殖蓝藻以生产商业产品(如生物燃料)非常感兴趣,但由于处理含有小而坚韧细胞的大体积液体的经济障碍,这些微生物的大规模培养受到阻碍。在Jordan等人(e00053-17)的一项研究中,蓝藻的分裂机制被可调地控制,以将生长过程与细胞分裂分离开来。作者表明,蓝藻可以被触发增加(cid:2) 3个数量级的大小,创造更适合收获和裂解的细胞。因此,他们表明,基因方法可以用来设计与生物处理设备更兼容的蓝藻,而不是相反。他们发现,这是一个关键的预测因子,抗树突芽胞杆菌细菌丰富度和患病率。表明含有多种抗真菌细菌,这些细菌在整个皮肤中各不相同,可能起到保护作用
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Articles of Significant Interest Selected from This Issue by the Editors
considerable interest in farming cyanobacteria for the production of commercial goods (e.g., biofuels), but scaled cultivation of these microbes is stymied by economic barriers to processing large liquid volumes containing small, tough cells. In a study by Jordan et al. (e00053-17), division machinery of cyanobacteria was tunably controlled to disentangle processes of growth from cell division. The authors show that cyanobacteria can be triggered to increase in size by (cid:2) 3 orders of magnitude, creating cells more amenable to harvest and lysis. As such, they show that genetic approaches can be used to engineer cyanobacteria that are more compatible with bioprocessing equipment, rather than vice versa. They found that was a key predictor of anti- B. dendrobatidis bacterial richness and prevalence. indicate that harbor diverse antifungal bacteria that vary across the and likely serve a protective
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来源期刊
Clinical and Vaccine Immunology
Clinical and Vaccine Immunology 医学-传染病学
CiteScore
2.88
自引率
0.00%
发文量
0
审稿时长
1.5 months
期刊介绍: Cessation. First launched as Clinical and Diagnostic Laboratory Immunology (CDLI) in 1994, CVI published articles that enhanced the understanding of the immune response in health and disease and after vaccination by showcasing discoveries in clinical, laboratory, and vaccine immunology. CVI was committed to advancing all aspects of vaccine research and immunization, including discovery of new vaccine antigens and vaccine design, development and evaluation of vaccines in animal models and in humans, characterization of immune responses and mechanisms of vaccine action, controlled challenge studies to assess vaccine efficacy, study of vaccine vectors, adjuvants, and immunomodulators, immune correlates of protection, and clinical trials.
期刊最新文献
Correction for Nishimori et al., “Identification of an Atypical Enzootic Bovine Leukosis in Japan by Using a Novel Classification of Bovine Leukemia Based on Immunophenotypic Analysis” GI-19007, a Novel Saccharomyces cerevisiae-Based Therapeutic Vaccine against Tuberculosis. High-Definition Mapping of Four Spatially Distinct Neutralizing Epitope Clusters on RiVax, a Candidate Ricin Toxin Subunit Vaccine. Progress toward Development of a Vaccine against Congenital Cytomegalovirus Infection. Stable Chromosomal Expression of Shigella flexneri 2a and 3a O-Antigens in the Live Salmonella Oral Vaccine Vector Ty21a.
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