巨马卓林溃疡切除术后下肢重建的可生物降解颞部基质

IF 1 Q4 CRITICAL CARE MEDICINE European burn journal Pub Date : 2022-11-22 DOI:10.3390/ebj3040045
Samuel MacDiarmid, Daniel Butler
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引用次数: 0

摘要

NovoSorb®可生物降解缓冲基质(BTM)是一种合成基质,用于某些复杂伤口的重建。我们报告一位先生,他持续严重的全层下肢烧伤,作为一个孩子,他接受了分厚皮肤移植的治疗。在后来的生活中,他继续发展为双侧无法愈合的溃疡,导致左侧膝盖以上截肢和巨大的环形右下肢鳞状细胞癌(SCC),包括大部分小腿。成功应用BTM实现了单个残肢的手术切除和保留。BTM已被证明在重建少量SCC伤口方面是成功的;然而,据我们所知,我们是第一个将其应用于与巨大下肢马卓林溃疡相关的圆周缺损重建的作者。
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Biodegradable Temporising Matrix for Lower Limb Reconstruction following the Resection of Giant Marjolin’s Ulcer
NovoSorb® Biodegradable Temporising Matrix (BTM) is a synthetic matrix used as an adjunct in the reconstruction of certain complex wounds. We present a gentleman who sustained severe full-thickness lower limb burns as a child which were treated with split-thickness skin grafts. In later life, he went on to develop bilateral non-healing ulcers, resulting in a left above-knee amputation and a giant circumferential right lower limb squamous cell carcinoma (SCC) encompassing the majority of the lower leg. Surgical resection and salvage of the single remaining limb was achieved with the successful application of a BTM. BTM has proven to be successful in reconstructing a small number of SCC wounds; however, to the best of our knowledge, we are the first authors to test its application in the reconstruction of a circumferential defect associated with a giant lower limb Marjolin’s ulcer.
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