拟合大脑功能连接的网络模型

Jagath Rajapakse, Sukrit Gupta, Xiuchao Sui
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引用次数: 7

摘要

功能磁共振成像(fMRI)可以研究人脑的功能连通性和功能网络的分层模块化结构。各种各样的网络模型,如幂律网络和模块化网络,已经被用来研究大脑网络。为了研究基于节点度和连接权分布的网络模型对功能性脑网络建模的可行性,我们将在Human Connectome Project中收集的静息状态fMRI扫描上计算几种网络模型的拟合优度。我们的实验表明幂律网络和随机块模型能很好地拟合受试者的功能连通性,随机块模型具有检测大脑功能模块的潜力。
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Fitting networks models for functional brain connectivity
Functional connectivity of the human brain and the hierarchical modular architecture of functional networks can be investigated using functional magnetic resonance imaging (fMRI). Various network models, such as power-law networks and modular networks have been explored before to study brain networks. In order to investigate the plausibility of modeling functional brain networks with network models based on distribution of node degree and connection weights, we will compute the goodness-of-fit of several network models on resting-state fMRI scans gathered in the Human Connectome Project. Our experiments suggest that the power-law networks and stochastic block models aptly fit functional connectivity of the subjects and the stochastic block models have the potential to detect functional modules of the brain.
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