巴基斯坦的登革热,从流行到地方病:治疗挑战、预防和当前事实

Ali H, Alvi A, Fatima S, Zafar F, Naveed S, Khan K, Ali U, Tariq A, Naqvi Gr, Mallick N
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引用次数: 12

摘要

登革热是一种重要的节肢动物传播的病毒感染,在世界范围内已经侵袭了人类。据估计,全球约有25亿居民受到这种感染的威胁。登革热已成为在亚热带和热带地区流行的易流行的病毒性疾病。登革热密切相关的血清型主要有四个特征:DENV-1、DENV-2、DENV-3和DENV-4。登革热通过被感染的雌性埃及伊蚊叮咬而传播。最常见的疾病包括;内出血、可能导致循环休克综合征的登革出血热(DHF)、高温、感冒样疾病、荨麻疹、严重关节痛、血小板减少症和血红素浓度升高。近年来,由于城市化为这些蚊子提供了理想的环境,包括室内排水孔中存在死水、饮用水受到污染、贫困、免疫力低下的个人和医疗设施不足,这种“断骨热”已成为巴基斯坦爆发的病毒性疾病。这些致病因素包括导致高死亡率和发病率的病毒性疾病。但如今,合理的处方和药物保健提供的设施已成为卫生保健的必要因素,以实现明确的结果,可以改善病人的生活质量。
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Dengue Fever in Pakistan, Episodes of Epidemic to Endemic: Treatment Challenges, Prevention and Current Facts
Dengue a majorly imperative arthropod-borne infection of viral origin has stroked the humans Worldwide. It has been estimated that about 2.5 billion inhabitants are at threatened by this infection around the globe. Dengue fever has become pandemic-prone viral disease prevailing all over subtropical and tropical regions. Majorly four characteristics of closely related serotypes of dengue are DENV-1, DENV-2, DENV-3 and DENV-4. Dengue fevers pass on by the bite of an infected female Aedes aegypti mosquito. The topmost ailments include; internal bleeding, Dengue Hemorrhagic Fever (DHF) which may lead to Circulatory Shock Syndrome (CSS), high temperature, cold like illness, urticaria, severe joint pain, thrombocytopenia and heme-concentration. From the recent years, this "break-bone fever" has become out breaking viral disease in Pakistan because Urbanization provided the ideal environment for these mosquitoes which includes presence of stagnant water in indoor drainage holes, contaminated water for drinking, poverty, immune compromised individuals and insufficient medical facilities. Such causative factors embrace viral disease that brings about high rate of mortality and morbidity. But nowadays, rational prescribing and the facilities provided by pharmaceutical care has become necessary element of health care for achieving definite outcomes that can improve a patient's quality of life.
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