这是怎么发生的?烫伤性油脂烧伤后异种移植物转化为真皮支架

IF 1 Q4 CRITICAL CARE MEDICINE European burn journal Pub Date : 2022-08-05 DOI:10.3390/ebj3030035
Aurelie Tran, Elizabeth Windell, Luke Pumiglia, Amanda P Bettencourt, G. Vercruysse
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引用次数: 0

摘要

多年来,异种移植物和其他生物敷料一直是烧伤护理的一个组成部分。猪移植物不仅价格低廉,而且对于部分烧伤,与局部用药相比,还提供了避免痛苦的换药的额外好处。在这个案例中,我们讨论了一个患有深度部分厚度烧伤的患者,异种移植物用于初始伤口覆盖。该猪移植物意外合并,患者最终接受手术清创和自体再移植。该病例表明了对猪异种移植伤口愈合机制的理解存在差距,并提出了未来使用异种移植加速伤口愈合的创新潜力。
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How Did This Happen? Xenograft Conversion to Dermal Scaffolding after Scalding Grease Burn
Xenograft and other biologic dressings have been an integral part of burn care for many years. Porcine graft is both inexpensive and, for partial thickness burns, provides the additional benefit of avoiding painful dressing changes when compared with topical agents. In this case, we discuss a patient suffering from deep partial thickness burns for whom xenograft was used for initial wound coverage. This porcine graft became unexpectedly incorporated, and the patient ultimately underwent operative debridement and autologous re-grafting. The case demonstrates a gap in the understanding of wound-healing mechanisms around porcine xenografts and raises the potential for future innovation in expedited wound healing using xenografting.
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