声带内侧化治疗肺切除术后喉返神经功能障碍的疗效

M. E. Demirag, Ç. Tezel, V. Baysungur, S. Evman
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摘要

背景:评估肺切除术后声带功能障碍的发生率以及声带介质化时机对预防这些患者术后肺部并发症的影响。材料与方法:回顾性分析肺切除术后发生声带功能障碍(VCD)/单侧声带麻痹(UVCP)患者的术后肺部并发症(PPC)发生率和住院时间。共2740例患者行解剖性肺切除术。11例术前诊断为VCD的患者转至耳鼻喉科。间接喉镜检查证实了UVCP的诊断。结果:经间接喉镜检查确诊UVCP 8例(0.3%)。3例为左侧上肺叶切除术,5例为左侧全肺切除术。需要支气管镜检查的肺不张和肺炎是PPC, 3例(37.5%)患者出现。羟基磷灰石钙注射液6例,聚四氟乙烯植入术2例。发生PPC的患者从肺切除到介质化的平均时间为5.3天,未发生PPC的患者为3.6天(p = 0.011)。所有患者均在平均8.1(6-13)天内顺利出院。1例患者在第5个月需要再次注射羟基磷灰石钙。平均随访14.8个月,所有患者声带位置稳定。结论:对开胸后UVCP进行声带内侧化治疗是安全的。为了减少语音和呼吸并发症,必须在术后早期进行。
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Efficiency of vocal cord medialization for recurrent laryngeal nerve dysfunction following pulmonary resections
Background: Evaluating the incidence of postoperative vocal cord dysfunction after pulmonary resections and the impact of timing for vocal cord medialization on preventing postoperative pulmonary complications for these patients. Materials and Methods: Patients developing vocal cord dysfunction (VCD)/unilateral vocal cord paralysis (UVCP) after pulmonary resection were examined retrospectively, in terms of postoperative pulmonary complication (PPC) rates and hospital length of stay. Total of 2740 patients underwent anatomical pulmonary resection for malignancy. Eleven patients were referred to otolaryngology team with pre-diagnosis of VCD following the operation. UVCP diagnosis was confirmed with indirect laryngoscopic examination. Results: UVCP diagnosis was confirmed in 8 (0.3%) with indirect laryngoscopic examination. Performed resections were left upper lobectomy in 3 and left pneumonectomy in 5 patients. Atelectasis necessitating bronchoscopy and pneumonia were the PPC, seen in 3 (37.5%) patients. Calcium hydroxyapatite injection for 6 patients and polytetrafluoroethylene graft implantation for 2 patients was performed. Mean duration between pulmonary resection and medialization was 5.3 days in patients developing PPC and 3.6 days in patients with no PPC (p = 0.011). All patients were discharged within an average of 8.1 (6-13) days, uneventfully. One patient required re-injection of calcium hydroxyapatite on 5th month. Throughout a mean follow-up duration of 14.8 months, all patients had stable vocal cord position. Conclusions: Vocal cord medialization can be performed safely for postthoracotomy UVCP. In order to minimize phonetic and respiratory complications, this procedure must be applied on early postoperative period.
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