猫哮喘:过敏试验和特异性免疫治疗的贡献。约20例

C. Prost
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引用次数: 7

摘要

哮喘是猫的一种非常常见的呼吸系统疾病,在临床和病理方面与人类哮喘非常相似。过敏性哮喘是人类最常被诊断出来的形式,想必猫也一样。本研究涉及20只患有临床显著哮喘的猫,有适当的放射学和支气管肺泡细胞学证据,并进行了过敏检查。猫有反复咳嗽、喘息和呼气性呼吸困难的病史,需要定期口服或全身皮质治疗。在停止使用这些皮质激素并用吸入的皮质激素代替之后,研究人员对其中18只猫进行了皮肤测试。结果显示,其中15例对空气过敏原(主要为室内尘螨)致敏,对花粉的致敏较少。避免干猫粮导致三只猫对储存螨过敏的症状缓解。对12只猫进行了特异性免疫治疗。治疗6-9个月后,其中8例(67%)哮喘症状完全缓解。4只猫仍需要药物治疗,包括每周吸入支气管扩张剂和皮质激素2-3次。本研究阐明了致敏因子在猫哮喘中的作用,并证明了特异性治疗、避免或特异性免疫治疗的优势。
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L’asthme félin : apport des tests allergiques et de l’immunothérapie spécifique. À propos de 20 cas

Asthma is a very common respiratory disease in cats, being very similar to human asthma with regards to its clinical and pathological aspects. Allergic asthma is the form the most frequently diagnosed in humans and this is presumably the same for cats. The present study concerns 20 cats with clinically significant asthma, with appropriate radiological and broncho-alveolar cytological evidence for which an allergic workup had been carried out. The cats had a history of recurrent coughing episodes, wheezing and expiratory dyspnea for which regular oral or systemic corticotherapy was required. After these corticoids were stopped and replaced by inhaled corticoids, skin tests were done on 18 of the cats. The results showed sensitization to aeroallergens, mainly house dust mites, less often to pollen, in 15 of them. Avoidance of dry cat food resulted in remission of symptoms in three cats allergic to storage mites. Specific immunotherapy was prescribed for 12 cats. After 6–9 months of therapy, total remission of asthma symptoms was observed in eight (67%) of them. Four cats still required pharmacotherapy, including inhaled bronchodilator and corticoid 2–3 times per week. This study illustrates the role of an allergenic factor in feline asthma and demonstrates the advantage of a specific therapy, avoidance or specific immunotherapy.

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Editorial Board Page tournée et nouveaux rendez-vous L’enseignement de l’allergologie pendant les études médicales en France Toux chronique de l’adulte et reflux gastro-œsophagien Les frontières du bilan allergologique en allergo-anesthésie
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