紫荆花甲醇根提取物对后脑虫的驱虫活性评价

A. Jain
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引用次数: 0

摘要

以紫荆根甲醇提取物为试虫,分别以10、25、50mg/ml为试虫浓度,对其驱虫活性进行了研究。以蠕虫麻痹时间和死亡时间表示结果,并与阿苯达唑为参比标准,生理盐水为对照进行活性比较。麻痹时间和死亡时间呈剂量依赖性缩短。结果表明,紫荆粗甲醇根提取物具有明显的麻痹性和致虫性作用,其中高浓度(50 mg/ml)紫荆的驱虫活性最强。根作为驱虫剂的用途已经确定,建议进一步研究以分离出导致活性的活性原理。关键词:驱虫活性,白花菊,紫荆花
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EVALUATION OF ANTHELMINTIC ACTIVITY OF BAUHINIA VARIEGATA LINN METHANOLIC ROOT EXTRACT ON PHERETIMA POSTHUMA
Methanolic extracts from roots of Bauhinia variegata linn were investigated for their anthelmintic activity by using three concentrations (10, 25, & 50mg/ml) as test worms. Results were expressed in terms of time of paralysis and time of death of worms and the activity was compared with albendazole as reference standard & Normal saline served as control. Dose dependent decreased paralyzing time and death time was observed. The results of present study indicated that crude methanolic root extract significantly demonstrated paralysis and also caused death of worms especially at higher concentration of (50 mg/ml), Bauhinia variegata showed the best anthelmintic activity. The use of the roots as anthelmintic has been established and further studies are recommended to isolate the active principles answerable for the activity. KEYWORDS: Anthelmintic activity, Pheretima Posthuma, Bauhinia variegata linn
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