左截尾数据参数化方法性能评价及在Covid-19数据分析中的应用建议

M. Tekindal, H. Yonar, S. Kader
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摘要

目的:文献中经常遇到临床研究中常见的左删节数据。的确,特别是在食品、环境、微生物和生物化学领域。在本研究中,试图确定参数逆风险模型中左截尾数据负偏态分布之间的最合适分布。方法:在研究范围内,首先根据每个分布的不同参数对数据进行不删节处理。然后,在不同的审查率(15%、25%和35%)和不同的样本量(1000、2000和3000)下进行模拟研究,以确定最合适的分布。采用AIC、AICC、HQIC和CAIC信息标准比较分布性能。由于不可能研究所有可能场景的模拟,因此彼此相似的场景通常比其他场景更受欢迎。结果:在模拟结果中,对于参数逆风险模型中的左截尾数据,最合适的分布是广义逆威布尔分布、Log-Logistic分布、Log-Normal分布、逆正态分布和Gamma分布。研究还发现,与修正威布尔分布、广义威布尔分布、广义威布尔分布和柔性威布尔分布相比,marshall - olkin分布表现出更优越的性能。原木物流?在实际数据应用检验中给出了分析分布中最合适的结果。结论:考虑到下一阶段疫情需要进行更多的统计评估,在Covid-19疫情评估中使用审查数据分析具有相当的附加性。使用这种方法可以获得更好的估计,特别是在Covid-19数据分析中。
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Evaluation of Parametric Method Performance for Left-Censored Data and Recommendation of Using for Covid-19 Data Analysis
bjectives: Left-censored data, which is commonly seen in clinical studies, are frequently encountered in the litera?ture, especially in the fields of food, environment, microbiology, and biochemistry. In this study, the most appropriate distribution between the negatively skewed distributions for left-censored data in Parametric Inverse Hazard Models was tried to be determined. Methods: Within the scope of the study, firstly, the data were produced uncensored according to different parameters of each distribution. Then, simulation studies were carried out in different censorship rates (15%, 25% and 35%) and various sample sizes (1000, 2000 and 3000) in order to determine the most appropriate distribution. AIC, AICC, HQIC, and CAIC information criteria were employed to compare the distribution performances. Since it was not possible to study simulations of all possible scenarios, scenarios similar to each other were generally preferred over others. Results: In the simulation results, the most appropriate distributions to be used for left-censored data in Parametric Inverse Hazard Models were found as Generalized Inverse Weibull as well as Log-Logistic, Log-Normal, Inverse Normal and Gamma distributions. It was also detected that the Marshal-Olkin distribution revealed a superior performance compared to the Modified Weibull, Generalized Gamma, Gamma, and Flexible Weibull distributions. Log logistics dis?tribution gave the most appropriate result among the analyzed distributions in the examination made with real data application. Conclusion: The use of censored data analysis in evaluations in terms of Covid-19 is quite additive, considering that more statistical evaluation will be needed in the next period of the epidemic. Improved estimates can be obtained with this approach, especially in Covid-19 data analysis.
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