Our clinical experience on renal protection with custadiol solution during juxtarenal clamping in open repair of abdominal aorta aneurysm

Aim: Technological developments on endovascular stents have increased the percutaneous repair of abdominal aortic aneurysm(AAAs). Open repair of abdominal aneurysm remains as the first option for treatment of aneurysm with compromising necks that need suprarenal aortic clamping(SAC). Open surgical repair with suprarenal aortic clamping may be associated with renal ischemia that may lead into renal injury. Our study focused on our clinical experience on the use of custodiol solution for renal protection during open repair of abdominal aortic aneurysm with suprarenal aortic clamping. Material and Methods: Our study consisted of 25 patients who underwent open repair for abdominal aortic aneurysm with suprarenal aortic clamping. During the repair, cold custodiol solution was used for renal protection in all patients. Outcomes included postoperative renal functions, mortality, hospital stay, need of postoperative dialysis and readmission due to renal injury. Results: 2 (8%) of our patients died, 2 patients (8%) experienced acute renal injury, hemodialysis was required in 8 patients (32%). There were 3 cases of morbidity, which included ileus in one patient, pneumonia in one patient and wound infection in one patient. Graft interposition was performed in one patient (4%) while aortobifemoral bypass was performed in 24 patients (96%). Conclusion: In our clinical experience, cold custadiol solution has shown to be safe as a renal protective solution during suprarenal aortic clamping in open repair of abdominal aortic aneurysm with well-preserved perioperative renal functions.