基于深度卷积神经网络的脑电图睡眠阶段评分可解释性分析

A. Vilamala, Kristoffer Hougaard Madsen, L. K. Hansen
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引用次数: 127

摘要

睡眠研究对于诊断失眠、嗜睡症或睡眠呼吸暂停等睡眠障碍非常重要。他们依靠从原始的睡眠信号中手动对睡眠阶段进行评分,这是一项繁琐的视觉任务,需要训练有素的专业人员的工作量。因此,在过去的几年里,人们一直在努力研究基于机器学习技术的自动舞台评分。在这项工作中,我们采用多锥度频谱分析,从脑电图信号中创建视觉上可解释的睡眠模式图像,作为深度卷积网络的输入,训练用于解决视觉识别任务。作为迁移学习的一个工作示例,提出了一个能够准确地对未见过的新患者的睡眠阶段进行分类的系统。与最先进的结果相比,广泛使用的公开可用数据集中的评估具有优势,同时为结果的可视化解释提供了框架。
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Deep convolutional neural networks for interpretable analysis of EEG sleep stage scoring
Sleep studies are important for diagnosing sleep disorders such as insomnia, narcolepsy or sleep apnea. They rely on manual scoring of sleep stages from raw polisomnography signals, which is a tedious visual task requiring the workload of highly trained professionals. Consequently, research efforts to purse for an automatic stage scoring based on machine learning techniques have been carried out over the last years. In this work, we resort to multitaper spectral analysis to create visually interpretable images of sleep patterns from EEG signals as inputs to a deep convolutional network trained to solve visual recognition tasks. As a working example of transfer learning, a system able to accurately classify sleep stages in new unseen patients is presented. Evaluations in a widely-used publicly available dataset favourably compare to state-of-the-art results, while providing a framework for visual interpretation of outcomes.
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