新型吲哚苯并[b]噻吩键合吡啶多苯并咪唑的合成

The Open Organic Chemistry Journal Pub Date : 2011-12-14 DOI:10.2174/1874095201105010127

S. Kamila, Haribabu Ankati, Kimberly Mendoza, E. Biehl

{"title":"新型吲哚苯并[b]噻吩键合吡啶多苯并咪唑的合成","authors":"S. Kamila, Haribabu Ankati, Kimberly Mendoza, E. Biehl","doi":"10.2174/1874095201105010127","DOIUrl":null,"url":null,"abstract":"Pyridobenzimidazoles 6a-iwere synthesized in very good to excellent yields (81-96%) by the condensation of substituted N-phenyl-o-phenylenediamines 4a-d with indole/benzo(b)thiophene-3-aldehydes 5a-t inmethoxyethanol under reflux conditions. The diamines 4a-d were prepared byfirst treating 2-chloro-3-nitropyridine (1)with suitably substituted anilines 2a-d then reducing the resulting3-nitro-N-phenylpyridin-2-amines 3a-d with tin(II)chloride using microwave heating in each case.","PeriodicalId":23020,"journal":{"name":"The Open Organic Chemistry Journal","volume":"25 5 1","pages":"127-134"},"PeriodicalIF":0.0000,"publicationDate":"2011-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"11","resultStr":"{\"title\":\"Synthesis of Novel Pyridobenzimidazoles Bonded to Indoleorbenzo[b]thio-phenestructures\",\"authors\":\"S. Kamila, Haribabu Ankati, Kimberly Mendoza, E. Biehl\",\"doi\":\"10.2174/1874095201105010127\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Pyridobenzimidazoles 6a-iwere synthesized in very good to excellent yields (81-96%) by the condensation of substituted N-phenyl-o-phenylenediamines 4a-d with indole/benzo(b)thiophene-3-aldehydes 5a-t inmethoxyethanol under reflux conditions. The diamines 4a-d were prepared byfirst treating 2-chloro-3-nitropyridine (1)with suitably substituted anilines 2a-d then reducing the resulting3-nitro-N-phenylpyridin-2-amines 3a-d with tin(II)chloride using microwave heating in each case.\",\"PeriodicalId\":23020,\"journal\":{\"name\":\"The Open Organic Chemistry Journal\",\"volume\":\"25 5 1\",\"pages\":\"127-134\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2011-12-14\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"11\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The Open Organic Chemistry Journal\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.2174/1874095201105010127\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Open Organic Chemistry Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2174/1874095201105010127","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 11

摘要

以取代的n -苯基-邻苯二胺4a-d与吲哚/苯并(b)噻吩-3醛5a-t为原料，在回流条件下以81-96%的收率合成了吡并并咪唑6a- 1。首先用适当取代的苯胺2-a -d处理2-氯-3-硝基吡啶(1)，然后用氯化锡(II)微波加热还原得到3-硝基-n -苯基吡啶-2-胺3- a-d，制备了4 -a -d二胺。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

Synthesis of Novel Pyridobenzimidazoles Bonded to Indoleorbenzo[b]thio-phenestructures

Pyridobenzimidazoles 6a-iwere synthesized in very good to excellent yields (81-96%) by the condensation of substituted N-phenyl-o-phenylenediamines 4a-d with indole/benzo(b)thiophene-3-aldehydes 5a-t inmethoxyethanol under reflux conditions. The diamines 4a-d were prepared byfirst treating 2-chloro-3-nitropyridine (1)with suitably substituted anilines 2a-d then reducing the resulting3-nitro-N-phenylpyridin-2-amines 3a-d with tin(II)chloride using microwave heating in each case.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

The Open Organic Chemistry Journal

自引率

0.00%

发文量